Publikation: Toward Increased Reliability, Transparency, and Accessibility in Cross-linking Mass Spectrometry
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Cross-linking mass spectrometry (MS) has substantially matured as a method over the past 2 decades through parallel development in multiple labs, demonstrating its applicability to protein structure determination, conformation analysis, and mapping protein interactions in complex mixtures. Cross-linking MS has become a much-appreciated and routinely applied tool, especially in structural biology. Therefore, it is timely that the community commits to the development of methodological and reporting standards. This white paper builds on an open process comprising a number of events at community conferences since 2015 and identifies aspects of Cross-linking MS for which guidelines should be developed as part of a Cross-linking MS standards initiative.
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LEITNER, Alexander, Alexandre M. J. J. BONVIN, Christoph H. BORCHERS, Robert J. CHALKLEY, Julia CHAMOT-ROOKE, Colin W. COMBE, Jürgen COX, Meng-Qiu DONG, Florian STENGEL, Juri RAPPSILBER, 2020. Toward Increased Reliability, Transparency, and Accessibility in Cross-linking Mass Spectrometry. In: Structure. Cell Press. 2020, 28(11), pp. 1259-1268. ISSN 0969-2126. eISSN 1878-4186. Available under: doi: 10.1016/j.str.2020.09.011BibTex
@article{Leitner2020-11-03Towar-52854, year={2020}, doi={10.1016/j.str.2020.09.011}, title={Toward Increased Reliability, Transparency, and Accessibility in Cross-linking Mass Spectrometry}, number={11}, volume={28}, issn={0969-2126}, journal={Structure}, pages={1259--1268}, author={Leitner, Alexander and Bonvin, Alexandre M. J. J. and Borchers, Christoph H. and Chalkley, Robert J. and Chamot-Rooke, Julia and Combe, Colin W. and Cox, Jürgen and Dong, Meng-Qiu and Stengel, Florian and Rappsilber, Juri} }
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