Publikation:

Analysis of asymmetries in ictal and inter-ictal SPECT images for the localization of epileptic foci

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2010

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Mathers, Christian
Wright, Thomas
Kuwert, Torsten
Platsch, Günther

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http://nbn-resolving.de/urn:nbn:de:bsz:352-186532
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https://doi.org/10.1109/NSSMIC.2010.5874202
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IEEE Nuclear Science Symposuim & Medical Imaging Conference. IEEE, 2010, pp. 2338-2341. ISBN 978-1-4244-9106-3. Available under: doi: 10.1109/NSSMIC.2010.5874202

Zusammenfassung

In patients suffering from focal epilepsy, the region of seizure onset is characterized by hyperperfusion during the seizure (ictal state), and hypoperfusion in normal (inter-ictal) state. For diagnosis and surgery planning in epilepsy patients, ictal and inter-ictal SPECT images play a major role. However, comparison of this kind of data is a difficult clinical problem due to varying physiological uptake in brain regions. For this reason, different analysis methods such as standard reading by a clinical expert, comparison to a normal database, subtraction ictal SPECT co-registered to MRI (SISCOM) or asymmetry analysis are applied, for a comprehensive analysis of the data. The latter is usually hampered by functional and anatomical asymmetries which aggravate analysis. For this reason, a novel approach for asymmetry analysis is presented in this work, which overcomes the aforementioned limitations. The approach was successfully applied to SPECT datasets of 10 epilepsy patients.

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004 Informatik

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2010 IEEE Nuclear Science Symposium and Medical Imaging Conference (2010 NSS/MIC), 30. Okt. 2010 - 6. Nov. 2010, Knoxville, TN
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ISO 690MERHOF, Dorit, Christian MATHERS, Thomas WRIGHT, Torsten KUWERT, Günther PLATSCH, 2010. Analysis of asymmetries in ictal and inter-ictal SPECT images for the localization of epileptic foci. 2010 IEEE Nuclear Science Symposium and Medical Imaging Conference (2010 NSS/MIC). Knoxville, TN, 30. Okt. 2010 - 6. Nov. 2010. In: IEEE Nuclear Science Symposuim & Medical Imaging Conference. IEEE, 2010, pp. 2338-2341. ISBN 978-1-4244-9106-3. Available under: doi: 10.1109/NSSMIC.2010.5874202
BibTex
@inproceedings{Merhof2010-10Analy-18653,
  year={2010},
  doi={10.1109/NSSMIC.2010.5874202},
  title={Analysis of asymmetries in ictal and inter-ictal SPECT images for the localization of epileptic foci},
  isbn={978-1-4244-9106-3},
  publisher={IEEE},
  booktitle={IEEE Nuclear Science Symposuim & Medical Imaging Conference},
  pages={2338--2341},
  author={Merhof, Dorit and Mathers, Christian and Wright, Thomas and Kuwert, Torsten and Platsch, Günther}
}
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