Publikation:

A beta/gamma Motif to Mimic alpha-Helical Turns in Proteins

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Datum

2010

Autor:innen

Araghi, Raheleh Rezaei
Jäckel, Christian
Salwiczek, Mario
Wagner, Sara C.
Wieczorek, Sebastian
Baldauf, Carsten
Koksch, Beate

Herausgeber:innen

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URI (zitierfähiger Link)
http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-128123
DOI (zitierfähiger Link)
https://doi.org/10.1002/cbic.200900700
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Urheberrechtlich geschützt

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Open Access-Veröffentlichung
Open Access Green

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Chemie: Publikationen
Core Facility der Universität Konstanz

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Titel in einer weiteren Sprache

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Zeitschriftenartikel
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Published

Erschienen in

ChemBioChem. 2010, 11(3), pp. 335-339. ISSN 1439-4227. eISSN 1439-7633. Available under: doi: 10.1002/cbic.200900700

Zusammenfassung

The combination of the properties of β- and γ-amino acids produce extended artificial fragments that recreate the properties of a natural α-helix. The substitution of two α-helical turns in an otherwise natural coiled-coil motif by a fragment of alternating β and γ-amino acids with retention of global conformation and stability of the fold was established. The new chimeric system shows a high potency in helical quaternary structure formation.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
540 Chemie

Schlagwörter

alpha-helical coiled coil, beta/gamma-peptides, foldamers, peptidomimetics, protein design

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ISO 690ARAGHI, Raheleh Rezaei, Christian JÄCKEL, Helmut CÖLFEN, Mario SALWICZEK, Antje VÖLKEL, Sara C. WAGNER, Sebastian WIECZOREK, Carsten BALDAUF, Beate KOKSCH, 2010. A beta/gamma Motif to Mimic alpha-Helical Turns in Proteins. In: ChemBioChem. 2010, 11(3), pp. 335-339. ISSN 1439-4227. eISSN 1439-7633. Available under: doi: 10.1002/cbic.200900700
BibTex
@article{Araghi2010betag-9806,
  year={2010},
  doi={10.1002/cbic.200900700},
  title={A beta/gamma Motif to Mimic alpha-Helical Turns in Proteins},
  number={3},
  volume={11},
  issn={1439-4227},
  journal={ChemBioChem},
  pages={335--339},
  author={Araghi, Raheleh Rezaei and Jäckel, Christian and Cölfen, Helmut and Salwiczek, Mario and Völkel, Antje and Wagner, Sara C. and Wieczorek, Sebastian and Baldauf, Carsten and Koksch, Beate}
}
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