Publikation:

A beta/gamma Motif to Mimic alpha-Helical Turns in Proteins

Vorschaubild

Dateien

12812.pdf
12812.pdfGröße: 758.87 KBDownloads: 1256

Datum

2010

Autor:innen

Araghi, Raheleh Rezaei
Jäckel, Christian
Salwiczek, Mario
Wagner, Sara C.
Wieczorek, Sebastian
Baldauf, Carsten
Koksch, Beate

Herausgeber:innen

Kontakt

ISSN der Zeitschrift

Electronic ISSN

ISBN

Bibliografische Daten

Verlag

Schriftenreihe

Auflagebezeichnung

URI (zitierfähiger Link)
http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-128123
DOI (zitierfähiger Link)
https://doi.org/10.1002/cbic.200900700
ArXiv-ID

Internationale Patentnummer

Link zur Lizenz
Urheberrechtlich geschützt

Angaben zur Forschungsförderung

Projekt

Open Access-Veröffentlichung
Open Access Green

Sammlungen

Chemie: Publikationen
Core Facility der Universität Konstanz

Gesperrt bis

Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

ChemBioChem. 2010, 11(3), pp. 335-339. ISSN 1439-4227. eISSN 1439-7633. Available under: doi: 10.1002/cbic.200900700

Zusammenfassung

The combination of the properties of β- and γ-amino acids produce extended artificial fragments that recreate the properties of a natural α-helix. The substitution of two α-helical turns in an otherwise natural coiled-coil motif by a fragment of alternating β and γ-amino acids with retention of global conformation and stability of the fold was established. The new chimeric system shows a high potency in helical quaternary structure formation.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
540 Chemie

Schlagwörter

alpha-helical coiled coil, beta/gamma-peptides, foldamers, peptidomimetics, protein design

Konferenz

Rezension
undefined / . - undefined, undefined

Forschungsvorhaben

Organisationseinheiten

Zeitschriftenheft

Zugehörige Datensätze in KOPS

Zitieren

ISO 690ARAGHI, Raheleh Rezaei, Christian JÄCKEL, Helmut CÖLFEN, Mario SALWICZEK, Antje VÖLKEL, Sara C. WAGNER, Sebastian WIECZOREK, Carsten BALDAUF, Beate KOKSCH, 2010. A beta/gamma Motif to Mimic alpha-Helical Turns in Proteins. In: ChemBioChem. 2010, 11(3), pp. 335-339. ISSN 1439-4227. eISSN 1439-7633. Available under: doi: 10.1002/cbic.200900700
BibTex
@article{Araghi2010betag-9806,
  year={2010},
  doi={10.1002/cbic.200900700},
  title={A beta/gamma Motif to Mimic alpha-Helical Turns in Proteins},
  number={3},
  volume={11},
  issn={1439-4227},
  journal={ChemBioChem},
  pages={335--339},
  author={Araghi, Raheleh Rezaei and Jäckel, Christian and Cölfen, Helmut and Salwiczek, Mario and Völkel, Antje and Wagner, Sara C. and Wieczorek, Sebastian and Baldauf, Carsten and Koksch, Beate}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/9806">
    <dcterms:bibliographicCitation>First publ. in: ChemBioChem 11 (2010), 3, pp. 335-339</dcterms:bibliographicCitation>
    <dc:creator>Araghi, Raheleh Rezaei</dc:creator>
    <dc:contributor>Wieczorek, Sebastian</dc:contributor>
    <dc:contributor>Salwiczek, Mario</dc:contributor>
    <dc:format>application/pdf</dc:format>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <dc:creator>Cölfen, Helmut</dc:creator>
    <dc:contributor>Cölfen, Helmut</dc:contributor>
    <dcterms:abstract xml:lang="eng">The combination of the properties of β- and γ-amino acids produce extended artificial fragments that recreate the properties of a natural α-helix. The substitution of two α-helical turns in an otherwise natural coiled-coil motif by a fragment of alternating β and γ-amino acids with retention of global conformation and stability of the fold was established. The new chimeric system shows a high potency in helical quaternary structure formation.</dcterms:abstract>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T18:14:32Z</dcterms:available>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:contributor>Wagner, Sara C.</dc:contributor>
    <dc:contributor>Baldauf, Carsten</dc:contributor>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dc:rights>terms-of-use</dc:rights>
    <dc:contributor>Koksch, Beate</dc:contributor>
    <dcterms:issued>2010</dcterms:issued>
    <dc:contributor>Araghi, Raheleh Rezaei</dc:contributor>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/9806"/>
    <dc:creator>Wieczorek, Sebastian</dc:creator>
    <dc:creator>Jäckel, Christian</dc:creator>
    <dc:language>eng</dc:language>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/9806/1/12812.pdf"/>
    <dc:creator>Völkel, Antje</dc:creator>
    <dcterms:title>A beta/gamma Motif to Mimic alpha-Helical Turns in Proteins</dcterms:title>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <dc:creator>Wagner, Sara C.</dc:creator>
    <dc:creator>Baldauf, Carsten</dc:creator>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T18:14:32Z</dc:date>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/9806/1/12812.pdf"/>
    <dc:contributor>Völkel, Antje</dc:contributor>
    <dc:contributor>Jäckel, Christian</dc:contributor>
    <dc:creator>Salwiczek, Mario</dc:creator>
    <dc:creator>Koksch, Beate</dc:creator>
  </rdf:Description>
</rdf:RDF>

Interner Vermerk

xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter

Kontakt
URL der Originalveröffentl.

Prüfdatum der URL

Prüfungsdatum der Dissertation

Finanzierungsart

Kommentar zur Publikation

Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Diese Publikation teilen