Publikation:

Asymmetric Synthesis of (S)-(-)-Acromelobic Acid

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2003

Autor:innen

Wild, Nicole

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Published

Erschienen in

European Journal of Organic Chemistry. 2003, 2003(22), pp. 4445-4449. ISSN 0075-4617. eISSN 0365-5490

Zusammenfassung

(S)-(-)-Acromelobic acid (1) was synthesized in nine steps in enantiomerically pure form from citrazinic acid (4) in an overall yield of 21%. The key steps of this synthesis are the introduction of the amino function by the bis(lactim) ether method and the introduction of the acid function by Stille coupling.

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Fachgebiet (DDC)
540 Chemie

Schlagwörter

Asymmetric synthesis, Amino acids, Natural products, Stille coupling, Protecting groups

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ISO 690WILD, Nicole, Ulrich GROTH, 2003. Asymmetric Synthesis of (S)-(-)-Acromelobic Acid. In: European Journal of Organic Chemistry. 2003, 2003(22), pp. 4445-4449. ISSN 0075-4617. eISSN 0365-5490
BibTex
@article{Wild2003Asymm-9629,
  year={2003},
  title={Asymmetric Synthesis of (S)-(-)-Acromelobic Acid},
  number={22},
  volume={2003},
  issn={0075-4617},
  journal={European Journal of Organic Chemistry},
  pages={4445--4449},
  author={Wild, Nicole and Groth, Ulrich}
}
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