Publikation: Asymmetric Synthesis of (S)-(-)-Acromelobic Acid
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2003
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Wild, Nicole
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European Journal of Organic Chemistry. 2003, 2003(22), pp. 4445-4449. ISSN 0075-4617. eISSN 0365-5490
Zusammenfassung
(S)-(-)-Acromelobic acid (1) was synthesized in nine steps in enantiomerically pure form from citrazinic acid (4) in an overall yield of 21%. The key steps of this synthesis are the introduction of the amino function by the bis(lactim) ether method and the introduction of the acid function by Stille coupling.
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Fachgebiet (DDC)
540 Chemie
Schlagwörter
Asymmetric synthesis, Amino acids, Natural products, Stille coupling, Protecting groups
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ISO 690
WILD, Nicole, Ulrich GROTH, 2003. Asymmetric Synthesis of (S)-(-)-Acromelobic Acid. In: European Journal of Organic Chemistry. 2003, 2003(22), pp. 4445-4449. ISSN 0075-4617. eISSN 0365-5490BibTex
@article{Wild2003Asymm-9629, year={2003}, title={Asymmetric Synthesis of (S)-(-)-Acromelobic Acid}, number={22}, volume={2003}, issn={0075-4617}, journal={European Journal of Organic Chemistry}, pages={4445--4449}, author={Wild, Nicole and Groth, Ulrich} }
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