Publikation: Role of Mechanotransduction and Tension in T Cell Function
Lade...
Dateien
Datum
2018
Herausgeber:innen
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
URI (zitierfähiger Link)
DOI (zitierfähiger Link)
Internationale Patentnummer
Link zur Lizenz
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Open Access Gold
Sammlungen
Core Facility der Universität Konstanz
Titel in einer weiteren Sprache
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published
Erschienen in
Frontiers in Immunology. 2018, 9, 2638. eISSN 1664-3224. Available under: doi: 10.3389/fimmu.2018.02638
Zusammenfassung
T cell migration from blood to, and within lymphoid organs and tissue, as well as, T cell activation rely on complex biochemical signaling events. But T cell migration and activation also take place in distinct mechanical environments and lead to drastic morphological changes and reorganization of the acto-myosin cytoskeleton. In this review we discuss how adhesion proteins and the T cell receptor act as mechanosensors to translate these mechanical contexts into signaling events. We further discuss how cell tension could bring a significant contribution to the regulation of T cell signaling and function.
Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
570 Biowissenschaften, Biologie
Schlagwörter
Konferenz
Rezension
undefined / . - undefined, undefined
Zitieren
ISO 690
ROSSY, Jérémie, Julia M. LAUFER, Daniel F. LEGLER, 2018. Role of Mechanotransduction and Tension in T Cell Function. In: Frontiers in Immunology. 2018, 9, 2638. eISSN 1664-3224. Available under: doi: 10.3389/fimmu.2018.02638BibTex
@article{Rossy2018-11-15Mecha-44056,
year={2018},
doi={10.3389/fimmu.2018.02638},
title={Role of Mechanotransduction and Tension in T Cell Function},
volume={9},
journal={Frontiers in Immunology},
author={Rossy, Jérémie and Laufer, Julia M. and Legler, Daniel F.},
note={Article Number: 2638}
}RDF
<rdf:RDF
xmlns:dcterms="http://purl.org/dc/terms/"
xmlns:dc="http://purl.org/dc/elements/1.1/"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:bibo="http://purl.org/ontology/bibo/"
xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
xmlns:foaf="http://xmlns.com/foaf/0.1/"
xmlns:void="http://rdfs.org/ns/void#"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#" >
<rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/44056">
<dc:rights>Attribution 4.0 International</dc:rights>
<dc:creator>Rossy, Jérémie</dc:creator>
<dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
<dc:contributor>Legler, Daniel F.</dc:contributor>
<dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2018-11-28T13:10:04Z</dc:date>
<dcterms:title>Role of Mechanotransduction and Tension in T Cell Function</dcterms:title>
<dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2018-11-28T13:10:04Z</dcterms:available>
<dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
<dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/44056/1/Rossy_2-184wwtnqy6z043.pdf"/>
<dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/44056/1/Rossy_2-184wwtnqy6z043.pdf"/>
<dcterms:rights rdf:resource="http://creativecommons.org/licenses/by/4.0/"/>
<void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
<dc:creator>Laufer, Julia M.</dc:creator>
<dc:contributor>Laufer, Julia M.</dc:contributor>
<dc:contributor>Rossy, Jérémie</dc:contributor>
<foaf:homepage rdf:resource="http://localhost:8080/"/>
<dcterms:issued>2018-11-15</dcterms:issued>
<dc:language>eng</dc:language>
<bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/44056"/>
<dc:creator>Legler, Daniel F.</dc:creator>
<dcterms:abstract xml:lang="eng">T cell migration from blood to, and within lymphoid organs and tissue, as well as, T cell activation rely on complex biochemical signaling events. But T cell migration and activation also take place in distinct mechanical environments and lead to drastic morphological changes and reorganization of the acto-myosin cytoskeleton. In this review we discuss how adhesion proteins and the T cell receptor act as mechanosensors to translate these mechanical contexts into signaling events. We further discuss how cell tension could bring a significant contribution to the regulation of T cell signaling and function.</dcterms:abstract>
</rdf:Description>
</rdf:RDF>Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Ja
