Publikation:

Wanda: a database of duplicated fish genes

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2002

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Peer, Yves van de
Taylor, John S.
Joseph, Jayabalan

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Nucleic Acids Research. 2002, 30(1), pp. 109-112. ISSN 0301-5610. eISSN 1362-4962

Zusammenfassung

Comparative genomics has shown that ray-finned fish (Actinopterygii) contain more copies of many genes than other vertebrates. A large number of these additional genes appear to have been produced during a genome duplication event that occurred early during the evolution of Actinopterygii (i.e. before the teleost radiation). In addition to this ancient genome duplication event, many lineages within Actinopterygii have experienced more recent genome duplications. Here we introduce a curated database named Wanda that lists groups of orthologous genes with one copy from man, mouse and chicken, one or two from tetraploid Xenopus and two or more ancient copies (i.e. paralogs) from ray-finned fish. The database also contains the sequence alignments and phylogenetic trees that were necessary for determining the correct orthologous and paralogous relationships among genes. Where available, map positions and functional data are also reported. The Wanda database should be of particular use to evolutionary and developmental biologists who are interested in the evolutionary and functional divergence of genes after duplication. Wanda is available at http:// www.evolutionsbiologie.uni-konstanz.de/Wanda/.

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570 Biowissenschaften, Biologie

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ISO 690PEER, Yves van de, John S. TAYLOR, Jayabalan JOSEPH, Axel MEYER, 2002. Wanda: a database of duplicated fish genes. In: Nucleic Acids Research. 2002, 30(1), pp. 109-112. ISSN 0301-5610. eISSN 1362-4962
BibTex
@article{Peer2002Wanda-8375,
  year={2002},
  title={Wanda: a database of duplicated fish genes},
  number={1},
  volume={30},
  issn={0301-5610},
  journal={Nucleic Acids Research},
  pages={109--112},
  author={Peer, Yves van de and Taylor, John S. and Joseph, Jayabalan and Meyer, Axel}
}
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