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Obsessive-compulsive severity spectrum in the community : prevalence, comorbidity, and course

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2004

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Angst, Jules
Gamma, Alex
Goodwin, Renee
Ajdacic, Vladeta
Eich, Dominique
Rössler, Wulf

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https://doi.org/10.1007/s00406-004-0459-4
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Psychologie: Publikationen
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Published

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European Archives of Psychiatry and Clinical Neurosciences. 2004, 254(3), pp. 156-164. ISSN 0940-1334. eISSN 1433-8491. Available under: doi: 10.1007/s00406-004-0459-4

Zusammenfassung

Objectives

To describe lifetime prevalence rates, course and comorbidity of obsessive-compulsive disorder (OCD), obsessive-compulsive syndromes (OCS) and OC-symptoms (OC-sx) up to age 41.

Methods

In the Zurich community cohort study 591 subjects were selected after screening at the age of 19 and studied prospectively by 6 interviews from 20 to 40; they represent 1599 subjects of the normal population. The diagnoses of OCD met DSM-IV criteria.Course was assessed by graphic illustrations and prospective data.

Results

The lifetime prevalence rate was 3.5 % for OCD (males 1.7%, females 5.4 %) and 8.7 % for OCS (males 9.9%, females 7.5 %). The onset of OC-sx was 18 years (median); and in 70% before age 20.OCD was treated in one third of cases, OCS in 6.1%. The course of symptoms was chronic in 60%,but OCD and OCS showed in most cases considerable improvements over time. OCD reduced quality of life mostly in the subject’s psychological wellbeing and at work but to a considerable extent also in other social roles. Comorbidity was prominent with bipolar disorder, panic disorder and social phobia and also significant with bulimia, binge eating, generalized anxiety disorder and suicide attempts; there was no association with substance abuse/dependence.

Conclusion

OCD and OCD are manifestations of a wide spectrum of severity with high prevalence and strong clinical validity. The long-term course is better than generally assumed.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
150 Psychologie

Schlagwörter

obsessive-compulsive disorder; obsessive-compulsive spectrum; prevalenc; ecomorbidity; course

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ISO 690ANGST, Jules, Alex GAMMA, Jérôme ENDRASS, Renee GOODWIN, Vladeta AJDACIC, Dominique EICH, Wulf RÖSSLER, 2004. Obsessive-compulsive severity spectrum in the community : prevalence, comorbidity, and course. In: European Archives of Psychiatry and Clinical Neurosciences. 2004, 254(3), pp. 156-164. ISSN 0940-1334. eISSN 1433-8491. Available under: doi: 10.1007/s00406-004-0459-4
BibTex
@article{Angst2004-06Obses-37711,
  year={2004},
  doi={10.1007/s00406-004-0459-4},
  title={Obsessive-compulsive severity spectrum in the community : prevalence, comorbidity, and course},
  number={3},
  volume={254},
  issn={0940-1334},
  journal={European Archives of Psychiatry and Clinical Neurosciences},
  pages={156--164},
  author={Angst, Jules and Gamma, Alex and Endrass, Jérôme and Goodwin, Renee and Ajdacic, Vladeta and Eich, Dominique and Rössler, Wulf}
}
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