Publikation:

4-Quinolone N-Oxides as Bacterial Weapons

Vorschaubild

Dateien

Zu diesem Dokument gibt es keine Dateien.

Datum

2018

Autor:innen

Szamosvari, David
Böttcher, Thomas

Herausgeber:innen

Kontakt

ISSN der Zeitschrift

Electronic ISSN

ISBN

Bibliografische Daten

Verlag

Schriftenreihe

Auflagebezeichnung

URI (zitierfähiger Link)
DOI (zitierfähiger Link)
https://doi.org/10.1055/s-0036-1591913
ArXiv-ID

Internationale Patentnummer

Angaben zur Forschungsförderung

Projekt

Open Access-Veröffentlichung

Sammlungen

Chemie: Publikationen
Zukunftskolleg: Publikationen
Core Facility der Universität Konstanz

Gesperrt bis

Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

Synlett. 2018, 29(05), pp. 542-547. ISSN 0936-5214. eISSN 1437-2096. Available under: doi: 10.1055/s-0036-1591913

Zusammenfassung

Various bacterial species are known to produce metabolites of the 4-quinolone N-oxide class. These compounds have antibiotic ­activities, and are believed to target the respiration of competing ­microbes by interfering with menaquinone-binding sites in enzymes of the electron-transport chain. Interestingly, even minor structural changes in related N-oxides produced by the same organism can produce a dramatic difference in antibiotic activity, suggesting possible functional specialization.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
540 Chemie

Schlagwörter

Pseudomonas, Burkholderia, respiratory chain, meta­bolites, cytochromes, antibiotics

Konferenz

Rezension
undefined / . - undefined, undefined

Forschungsvorhaben

Organisationseinheiten

Zeitschriftenheft

Zugehörige Datensätze in KOPS

Zitieren

ISO 690SZAMOSVARI, David, Thomas BÖTTCHER, 2018. 4-Quinolone N-Oxides as Bacterial Weapons. In: Synlett. 2018, 29(05), pp. 542-547. ISSN 0936-5214. eISSN 1437-2096. Available under: doi: 10.1055/s-0036-1591913
BibTex
@article{Szamosvari2018-03-024Quin-41747,
  year={2018},
  doi={10.1055/s-0036-1591913},
  title={4-Quinolone N-Oxides as Bacterial Weapons},
  number={05},
  volume={29},
  issn={0936-5214},
  journal={Synlett},
  pages={542--547},
  author={Szamosvari, David and Böttcher, Thomas}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/41747">
    <dc:creator>Szamosvari, David</dc:creator>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/52"/>
    <dc:contributor>Szamosvari, David</dc:contributor>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dcterms:title>4-Quinolone N-Oxides as Bacterial Weapons</dcterms:title>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/41747"/>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/52"/>
    <dc:contributor>Böttcher, Thomas</dc:contributor>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2018-03-13T08:08:34Z</dc:date>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <dcterms:issued>2018-03-02</dcterms:issued>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2018-03-13T08:08:34Z</dcterms:available>
    <dc:language>eng</dc:language>
    <dc:creator>Böttcher, Thomas</dc:creator>
    <dcterms:abstract xml:lang="eng">Various bacterial species are known to produce metabolites of the 4-quinolone N-oxide class. These compounds have antibiotic ­activities, and are believed to target the respiration of competing ­microbes by interfering with menaquinone-binding sites in enzymes of the electron-transport chain. Interestingly, even minor structural changes in related N-oxides produced by the same organism can produce a dramatic difference in antibiotic activity, suggesting possible functional specialization.</dcterms:abstract>
  </rdf:Description>
</rdf:RDF>

Interner Vermerk

xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter

Kontakt
URL der Originalveröffentl.

Prüfdatum der URL

Prüfungsdatum der Dissertation

Finanzierungsart

Kommentar zur Publikation

Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Ja
Diese Publikation teilen