Publikation:

The Rise of Three Rs Centres and Platforms in Europe

Lade...
Vorschaubild

Dateien

Neuhaus_2-1h0ub34r4i5532.pdf
Neuhaus_2-1h0ub34r4i5532.pdfGröße: 385.28 KBDownloads: 332

Datum

2022

Autor:innen

Neuhaus, Winfried
Reininger-Gutmann, Birgit
Rinner, Beate
Plasenzotti, Roberto
Wilflingseder, Doris
De Kock, Joery
Vanhaecke, Tamara
et al.

Herausgeber:innen

Kontakt

ISSN der Zeitschrift

Electronic ISSN

ISBN

Bibliografische Daten

Verlag

Schriftenreihe

Auflagebezeichnung

ArXiv-ID

Internationale Patentnummer

Angaben zur Forschungsförderung

Projekt

Research and harmonization activities to promote acceptance of animal-free new approach methods in different stakeholder communities (NAM-ACCEPT)
Open Access-Veröffentlichung
Open Access Green
Core Facility der Universität Konstanz

Gesperrt bis

Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

ATLA - Alternatives to Laboratory Animals. Sage. 2022, 50(2), pp. 90-120. ISSN 0261-1929. eISSN 2632-3559. Available under: doi: 10.1177/02611929221099165

Zusammenfassung

Public awareness and discussion about animal experiments and replacement methods has greatly increased in recent years. The term 'the Three Rs', which stands for the Replacement, Reduction and Refinement of animal experiments, is inseparably linked in this context. A common goal within the Three Rs scientific community is to develop predictive non-animal models and to better integrate all available data from in vitro, in silico and omics technologies into regulatory decision-making processes regarding, for example, the toxicity of chemicals, drugs or food ingredients. In addition, it is a general concern to implement (human) non-animal methods in basic research. Toward these efforts, there has been an ever-increasing number of Three Rs centres and platforms established over recent years - not only to develop novel methods, but also to disseminate knowledge and help to implement the Three Rs principles in policies and education. The adoption of Directive 2010/63/EU on the protection of animals used for scientific purposes gave a strong impetus to the creation of Three Rs initiatives, in the form of centres and platforms. As the first of a series of papers, this article gives an overview of the European Three Rs centres and platforms, and their historical development. The subsequent articles, to be published over the course of ATLA's 50th Anniversary year, will summarise the current focus and tasks as well as the future and the plans of the Three Rs centres and platforms. The Three Rs centres and platforms are very important points of contact and play an immense role in their respective countries as 'on the ground' facilitators of Directive 2010/63/EU. They are also invaluable for the widespread dissemination of information and for promoting implementation of the Three Rs in general.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
570 Biowissenschaften, Biologie

Schlagwörter

3R, 3Rs, EU3Rnet, NAM, NAMs, new approach methodologies, novel approach methodologies, non-animal methods

Konferenz

Rezension
undefined / . - undefined, undefined

Forschungsvorhaben

Organisationseinheiten

Zeitschriftenheft

Zugehörige Datensätze in KOPS

Zitieren

ISO 690NEUHAUS, Winfried, Birgit REININGER-GUTMANN, Beate RINNER, Roberto PLASENZOTTI, Doris WILFLINGSEDER, Joery DE KOCK, Tamara VANHAECKE, Thomas HARTUNG, Giorgia PALLOCCA, Marcel LEIST, 2022. The Rise of Three Rs Centres and Platforms in Europe. In: ATLA - Alternatives to Laboratory Animals. Sage. 2022, 50(2), pp. 90-120. ISSN 0261-1929. eISSN 2632-3559. Available under: doi: 10.1177/02611929221099165
BibTex
@article{Neuhaus2022-03Three-57596,
  year={2022},
  doi={10.1177/02611929221099165},
  title={The Rise of Three Rs Centres and Platforms in Europe},
  number={2},
  volume={50},
  issn={0261-1929},
  journal={ATLA - Alternatives to Laboratory Animals},
  pages={90--120},
  author={Neuhaus, Winfried and Reininger-Gutmann, Birgit and Rinner, Beate and Plasenzotti, Roberto and Wilflingseder, Doris and De Kock, Joery and Vanhaecke, Tamara and Hartung, Thomas and Pallocca, Giorgia and Leist, Marcel}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/57596">
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dcterms:abstract xml:lang="eng">Public awareness and discussion about animal experiments and replacement methods has greatly increased in recent years. The term 'the Three Rs', which stands for the Replacement, Reduction and Refinement of animal experiments, is inseparably linked in this context. A common goal within the Three Rs scientific community is to develop predictive non-animal models and to better integrate all available data from in vitro, in silico and omics technologies into regulatory decision-making processes regarding, for example, the toxicity of chemicals, drugs or food ingredients. In addition, it is a general concern to implement (human) non-animal methods in basic research. Toward these efforts, there has been an ever-increasing number of Three Rs centres and platforms established over recent years - not only to develop novel methods, but also to disseminate knowledge and help to implement the Three Rs principles in policies and education. The adoption of Directive 2010/63/EU on the protection of animals used for scientific purposes gave a strong impetus to the creation of Three Rs initiatives, in the form of centres and platforms. As the first of a series of papers, this article gives an overview of the European Three Rs centres and platforms, and their historical development. The subsequent articles, to be published over the course of ATLA's 50th Anniversary year, will summarise the current focus and tasks as well as the future and the plans of the Three Rs centres and platforms. The Three Rs centres and platforms are very important points of contact and play an immense role in their respective countries as 'on the ground' facilitators of Directive 2010/63/EU. They are also invaluable for the widespread dissemination of information and for promoting implementation of the Three Rs in general.</dcterms:abstract>
    <dc:contributor>Hartung, Thomas</dc:contributor>
    <dc:creator>Neuhaus, Winfried</dc:creator>
    <dc:contributor>Plasenzotti, Roberto</dc:contributor>
    <dc:contributor>De Kock, Joery</dc:contributor>
    <dc:contributor>Pallocca, Giorgia</dc:contributor>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/57596/1/Neuhaus_2-1h0ub34r4i5532.pdf"/>
    <dc:contributor>Leist, Marcel</dc:contributor>
    <dc:creator>Wilflingseder, Doris</dc:creator>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2022-05-20T06:59:01Z</dc:date>
    <dcterms:issued>2022-03</dcterms:issued>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2022-05-20T06:59:01Z</dcterms:available>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <dc:contributor>Rinner, Beate</dc:contributor>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/57596"/>
    <dc:creator>Rinner, Beate</dc:creator>
    <dc:creator>Vanhaecke, Tamara</dc:creator>
    <dc:contributor>Neuhaus, Winfried</dc:contributor>
    <dc:contributor>Vanhaecke, Tamara</dc:contributor>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:creator>Plasenzotti, Roberto</dc:creator>
    <dc:creator>Reininger-Gutmann, Birgit</dc:creator>
    <dc:creator>Hartung, Thomas</dc:creator>
    <dc:creator>Leist, Marcel</dc:creator>
    <dc:creator>De Kock, Joery</dc:creator>
    <dcterms:title>The Rise of Three Rs Centres and Platforms in Europe</dcterms:title>
    <dc:creator>Pallocca, Giorgia</dc:creator>
    <dc:rights>terms-of-use</dc:rights>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/57596/1/Neuhaus_2-1h0ub34r4i5532.pdf"/>
    <dc:contributor>Reininger-Gutmann, Birgit</dc:contributor>
    <dc:contributor>Wilflingseder, Doris</dc:contributor>
    <dc:language>eng</dc:language>
  </rdf:Description>
</rdf:RDF>

Interner Vermerk

xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter

Kontakt
URL der Originalveröffentl.

Prüfdatum der URL

Prüfungsdatum der Dissertation

Finanzierungsart

Kommentar zur Publikation

Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Ja
Diese Publikation teilen