Asymmetric Synthesis of Diastereomerically and Enantiomerically Pure, 3-Substituted (2S,3R)-N-Methylserine Esters

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dc.contributor.authorBeulshausen, Tessadeu
dc.contributor.authorGroth, Ulrich
dc.contributor.authorSchöllkopf, Ulrichdeu
dc.date.accessioned2011-03-24T18:13:35Zdeu
dc.date.available2011-03-24T18:13:35Zdeu
dc.date.issued1992deu
dc.description.abstractA novel method for the synthesis of N-methylserines has been developed. The oxazolidines 4 are formed by condensation of the serine methyl esters 1 with formaldehyde. These intermediates are subsequently reduced to the N-methylserine methyl esters 9 by an acid-catalyzed ring opening via their iminium ions 2 with triethylsilane/trifluoroacetic acid.deu
dc.description.versionpublished
dc.format.mimetypeapplication/pdfdeu
dc.identifier.citationFirst publ. in: Liebigs Annalen der Chemie 1992, 5, pp. 523-526deu
dc.identifier.doi10.1002/jlac.199219920190
dc.identifier.ppn276803906deu
dc.identifier.urihttp://kops.uni-konstanz.de/handle/123456789/9671
dc.language.isoengdeu
dc.legacy.dateIssued2008deu
dc.rightsAttribution-NonCommercial-NoDerivs 2.0 Generic
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.0/
dc.subjectSerine derivativesdeu
dc.subjectBislactim ether methoddeu
dc.subject.ddc540deu
dc.titleAsymmetric Synthesis of Diastereomerically and Enantiomerically Pure, 3-Substituted (2S,3R)-N-Methylserine Esterseng
dc.typeJOURNAL_ARTICLEdeu
dspace.entity.typePublication
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@article{Beulshausen1992Asymm-9671,
  year={1992},
  doi={10.1002/jlac.199219920190},
  title={Asymmetric Synthesis of Diastereomerically and Enantiomerically Pure, 3-Substituted (2S,3R)-N-Methylserine Esters},
  number={5},
  volume={1992},
  issn={0170-2041},
  journal={Liebigs Annalen der Chemie},
  pages={523--526},
  author={Beulshausen, Tessa and Groth, Ulrich and Schöllkopf, Ulrich}
}
kops.citation.iso690BEULSHAUSEN, Tessa, Ulrich GROTH, Ulrich SCHÖLLKOPF, 1992. Asymmetric Synthesis of Diastereomerically and Enantiomerically Pure, 3-Substituted (2S,3R)-N-Methylserine Esters. In: Liebigs Annalen der Chemie. 1992, 1992(5), pp. 523-526. ISSN 0170-2041. eISSN 1099-0690. Available under: doi: 10.1002/jlac.199219920190deu
kops.citation.iso690BEULSHAUSEN, Tessa, Ulrich GROTH, Ulrich SCHÖLLKOPF, 1992. Asymmetric Synthesis of Diastereomerically and Enantiomerically Pure, 3-Substituted (2S,3R)-N-Methylserine Esters. In: Liebigs Annalen der Chemie. 1992, 1992(5), pp. 523-526. ISSN 0170-2041. eISSN 1099-0690. Available under: doi: 10.1002/jlac.199219920190eng
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