StochNetV2 : A Tool for Automated Deep Abstractions for Stochastic Reaction Networks

Repin, Denis; Phung, Nhat-Huy; Petrov, Tatjana

StochNetV2 : A Tool for Automated Deep Abstractions for Stochastic Reaction Networks

Dateien

Zu diesem Dokument gibt es keine Dateien.

Datum

2020

Autor:innen

Repin, Denis

Phung, Nhat-Huy

Petrov, Tatjana

DOI (zitierfähiger Link)

https://doi.org/10.1007/978-3-030-59854-9_4

Sammlungen

Informatik und Informationswissenschaft

Publikationstyp

Beitrag zu einem Konferenzband

Publikationsstatus

Published

Erschienen in

GRIBAUDO, Marco, ed., David N. JANSEN, ed., Anne REMKE, ed.. Quantitative Evaluation of Systems : 17th International Conference, QEST 2020, Vienna, Austria, August 31 - September 3, 2020, Proceedings. Cham: Springer, 2020, pp. 27-32. ISSN 0302-9743. eISSN 1611-3349. ISBN 978-3-030-59853-2. Available under: doi: 10.1007/978-3-030-59854-9_4

Zusammenfassung

We present a toolbox for stochastic simulations with CRN models and their (automated) deep abstractions: a mixture density deep neural network trained on time-series data produced by the CRN. The optimal neural network architecture is learnt along with learning the transition kernel of the abstract process. Automated search of the architecture makes the method applicable directly to any given CRN, which is time-saving for deep learning experts and crucial for non-specialists. The tool was primarily designed to efficiently reproduce simulation traces of given complex stochastic reaction networks arising in systems biology research, possibly with multi-modal emergent phenotypes. It is at the same time applicable to any other application domain, where time-series measurements of a Markovian stochastic process are available by experiment or synthesised with simulation (e.g. are obtained from a rule-based description of the CRN).

Fachgebiet (DDC)

004 Informatik

Konferenz

17th International Conference, QEST 2020, 31. Aug. 2020 - 3. Sep. 2020, Wien

Zitieren

ISO 690

REPIN, Denis, Nhat-Huy PHUNG, Tatjana PETROV, 2020. StochNetV2 : A Tool for Automated Deep Abstractions for Stochastic Reaction Networks. 17th International Conference, QEST 2020. Wien, 31. Aug. 2020 - 3. Sep. 2020. In: GRIBAUDO, Marco, ed., David N. JANSEN, ed., Anne REMKE, ed.. Quantitative Evaluation of Systems : 17th International Conference, QEST 2020, Vienna, Austria, August 31 - September 3, 2020, Proceedings. Cham: Springer, 2020, pp. 27-32. ISSN 0302-9743. eISSN 1611-3349. ISBN 978-3-030-59853-2. Available under: doi: 10.1007/978-3-030-59854-9_4

BibTex

@inproceedings{Repin2020Stoch-51770,
  year={2020},
  doi={10.1007/978-3-030-59854-9_4},
  title={StochNetV2 : A Tool for Automated Deep Abstractions for Stochastic Reaction Networks},
  number={12289},
  isbn={978-3-030-59853-2},
  issn={0302-9743},
  publisher={Springer},
  address={Cham},
  series={Lecture Notes in Computer Science},
  booktitle={Quantitative Evaluation of Systems : 17th International Conference, QEST 2020, Vienna, Austria, August 31 - September 3, 2020, Proceedings},
  pages={27--32},
  editor={Gribaudo, Marco and Jansen, David N. and Remke, Anne},
  author={Repin, Denis and Phung, Nhat-Huy and Petrov, Tatjana}
}

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Universitätsbibliographie

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