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From Bioconjugation to self-assembly in Nanobiotechnology : quantum dots trapped and stabilized by Toroid Protein Yoctowells

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Schreiber_226312.pdf
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2012

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Schreiber, Andreas
Yuan, Ying
Huber, Matthias C.
Thomann, Ralf
Ziegler, Andreas
Dengjel, Jörn
Schiller, Stefan M.

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Advanced Engineering Materials. 2012, 14(6), pp. B344-B350. ISSN 1438-1656. eISSN 1527-2648. Available under: doi: 10.1002/adem.201180083

Zusammenfassung

Conjugation of quantum dots (QDs) with proteins is applicable for biosensing and imaging in biomedical applications but also for the confined assembly of various nanostructures. Here, the conjugation of CdSe QDs ranging from 2.5 up to 9.5 nm with Hcp1, a yoctowell forming hexameric core protein of Pseudomonas aeruginosa, is described. Defined structures ranging from single QDs trapped within the donut-shaped hexameric protein cavity over "globular" multi-toroid architectures up to photonic wires of 850 nm in length and 9 nm in width are self-assembled while preserving the native hexameric structure of the protein conserving the photoluminescence intensity of the QDs in aqueous solution for more than 3 month.

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540 Chemie

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ISO 690SCHREIBER, Andreas, Ying YUAN, Matthias C. HUBER, Ralf THOMANN, Andreas ZIEGLER, Helmut CÖLFEN, Jörn DENGJEL, Michael KRÜGER, Stefan M. SCHILLER, 2012. From Bioconjugation to self-assembly in Nanobiotechnology : quantum dots trapped and stabilized by Toroid Protein Yoctowells. In: Advanced Engineering Materials. 2012, 14(6), pp. B344-B350. ISSN 1438-1656. eISSN 1527-2648. Available under: doi: 10.1002/adem.201180083
BibTex
@article{Schreiber2012Bioco-22631,
  year={2012},
  doi={10.1002/adem.201180083},
  title={From Bioconjugation to self-assembly in Nanobiotechnology : quantum dots trapped and stabilized by Toroid Protein Yoctowells},
  number={6},
  volume={14},
  issn={1438-1656},
  journal={Advanced Engineering Materials},
  pages={B344--B350},
  author={Schreiber, Andreas and Yuan, Ying and Huber, Matthias C. and Thomann, Ralf and Ziegler, Andreas and Cölfen, Helmut and Dengjel, Jörn and Krüger, Michael and Schiller, Stefan M.}
}
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