Publikation:

Bispecific antibodies come to the aid of cancer immunotherapy

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Amelio_2-1syym271fngfm8.pdf
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2021

Autor:innen

Melino, Gerry
Levine, Arnold J.

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Published

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Molecular Oncology. Wiley. 2021, 15(7), pp. 1759-1763. ISSN 1574-7891. eISSN 1878-0261. Available under: doi: 10.1002/1878-0261.12977

Zusammenfassung

Three collaborative studies published by the groups of Vogelstein, Gabelli, and Zhou report the development of specially designed bispecific antibodies that may help in overcoming the limitations of current immunotherapies. The bispecific antibodies have been designed to couple cells harboring HLA-presented tumor-specific antigens from Tp53 mutant or Ras mutant with CD4 and CD8 T cells, thus facilitating immune-mediated clearance of the cancer cells.

Zusammenfassung in einer weiteren Sprache

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570 Biowissenschaften, Biologie

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ISO 690AMELIO, Ivano, Gerry MELINO, Arnold J. LEVINE, 2021. Bispecific antibodies come to the aid of cancer immunotherapy. In: Molecular Oncology. Wiley. 2021, 15(7), pp. 1759-1763. ISSN 1574-7891. eISSN 1878-0261. Available under: doi: 10.1002/1878-0261.12977
BibTex
@article{Amelio2021Bispe-56464,
  year={2021},
  doi={10.1002/1878-0261.12977},
  title={Bispecific antibodies come to the aid of cancer immunotherapy},
  number={7},
  volume={15},
  issn={1574-7891},
  journal={Molecular Oncology},
  pages={1759--1763},
  author={Amelio, Ivano and Melino, Gerry and Levine, Arnold J.}
}
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