Publikation: Memory signals from the thalamus : Early thalamocortical phase synchronization entrains gamma oscillations during long-term memory retrieval
Dateien
Datum
Autor:innen
Herausgeber:innen
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
DOI (zitierfähiger Link)
Internationale Patentnummer
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Core Facility der Universität Konstanz
Titel in einer weiteren Sprache
Publikationstyp
Publikationsstatus
Erschienen in
Zusammenfassung
The thalamus is believed to be a key node in human memory networks, however, very little is known about its real-time functional role. Here we examined the dynamics of thalamocortical communication during long-term episodic memory retrieval in two experiments. In Experiment 1, intrathalamic and surface EEG was recorded in an epileptic patient implanted with depth electrodes for brain stimulation therapy. In a recognition memory test, early (300–500 ms) stimulus-linked oscillatory synchrony between mediodorsal thalamic and frontal surface electrodes at beta frequency (20 Hz) was enhanced for correctly remembered old compared to correctly rejected new items. Directionality measures (Granger causality) indicated that the thalamus was the sender, and the neocortex the receiver, of this beta signal, which also modulated the power of neocortical gamma (55–80 Hz) oscillations (cross-frequency coupling). Experiment 2 validated the cross-frequency coupling effects in a healthy participant sample. Confirming the findings from Experiment 1, significantly increased cross-frequency coupling was found over frontal scalp electrodes during successful recognition. Extending anatomical knowledge on thalamic connectivity with frontal neocortex, these results suggest that the thalamus sends an early memory signal to frontal regions, triggering further memory search processes.
Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
Schlagwörter
Konferenz
Rezension
Zitieren
ISO 690
STAUDIGL, Tobias, Tino ZAEHLE, Jürgen VOGES, Simon HANSLMAYR, Christine ESSLINGER, Hermann HINRICHS, Friedhelm C. SCHMITT, Hans-Jochen HEINZE, Alan RICHARDSON-KLAVEHN, 2012. Memory signals from the thalamus : Early thalamocortical phase synchronization entrains gamma oscillations during long-term memory retrieval. In: Neuropsychologia. Elsevier. 2012, 50(14), pp. 3519-3527. ISSN 0028-3932. eISSN 1873-3514. Available under: doi: 10.1016/j.neuropsychologia.2012.08.023BibTex
@article{Staudigl2012-12Memor-48983, year={2012}, doi={10.1016/j.neuropsychologia.2012.08.023}, title={Memory signals from the thalamus : Early thalamocortical phase synchronization entrains gamma oscillations during long-term memory retrieval}, number={14}, volume={50}, issn={0028-3932}, journal={Neuropsychologia}, pages={3519--3527}, author={Staudigl, Tobias and Zaehle, Tino and Voges, Jürgen and Hanslmayr, Simon and Esslinger, Christine and Hinrichs, Hermann and Schmitt, Friedhelm C. and Heinze, Hans-Jochen and Richardson-Klavehn, Alan} }
RDF
<rdf:RDF xmlns:dcterms="http://purl.org/dc/terms/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:bibo="http://purl.org/ontology/bibo/" xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#" xmlns:foaf="http://xmlns.com/foaf/0.1/" xmlns:void="http://rdfs.org/ns/void#" xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/48983"> <dc:contributor>Schmitt, Friedhelm C.</dc:contributor> <dc:contributor>Voges, Jürgen</dc:contributor> <dc:contributor>Heinze, Hans-Jochen</dc:contributor> <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-03-10T11:57:26Z</dc:date> <dc:language>eng</dc:language> <dc:creator>Hanslmayr, Simon</dc:creator> <dc:creator>Staudigl, Tobias</dc:creator> <dc:creator>Zaehle, Tino</dc:creator> <dc:contributor>Hanslmayr, Simon</dc:contributor> <dc:contributor>Staudigl, Tobias</dc:contributor> <dc:creator>Hinrichs, Hermann</dc:creator> <dc:creator>Richardson-Klavehn, Alan</dc:creator> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/> <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2020-03-10T11:57:26Z</dcterms:available> <dc:contributor>Richardson-Klavehn, Alan</dc:contributor> <dc:creator>Voges, Jürgen</dc:creator> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/52"/> <dc:contributor>Esslinger, Christine</dc:contributor> <dc:contributor>Zaehle, Tino</dc:contributor> <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/52"/> <dcterms:abstract xml:lang="eng">The thalamus is believed to be a key node in human memory networks, however, very little is known about its real-time functional role. Here we examined the dynamics of thalamocortical communication during long-term episodic memory retrieval in two experiments. In Experiment 1, intrathalamic and surface EEG was recorded in an epileptic patient implanted with depth electrodes for brain stimulation therapy. In a recognition memory test, early (300–500 ms) stimulus-linked oscillatory synchrony between mediodorsal thalamic and frontal surface electrodes at beta frequency (20 Hz) was enhanced for correctly remembered old compared to correctly rejected new items. Directionality measures (Granger causality) indicated that the thalamus was the sender, and the neocortex the receiver, of this beta signal, which also modulated the power of neocortical gamma (55–80 Hz) oscillations (cross-frequency coupling). Experiment 2 validated the cross-frequency coupling effects in a healthy participant sample. Confirming the findings from Experiment 1, significantly increased cross-frequency coupling was found over frontal scalp electrodes during successful recognition. Extending anatomical knowledge on thalamic connectivity with frontal neocortex, these results suggest that the thalamus sends an early memory signal to frontal regions, triggering further memory search processes.</dcterms:abstract> <dc:creator>Esslinger, Christine</dc:creator> <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/> <dcterms:title>Memory signals from the thalamus : Early thalamocortical phase synchronization entrains gamma oscillations during long-term memory retrieval</dcterms:title> <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/> <dcterms:issued>2012-12</dcterms:issued> <dc:creator>Heinze, Hans-Jochen</dc:creator> <dc:creator>Schmitt, Friedhelm C.</dc:creator> <foaf:homepage rdf:resource="http://localhost:8080/"/> <dc:contributor>Hinrichs, Hermann</dc:contributor> <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/48983"/> </rdf:Description> </rdf:RDF>