The DEK Protein : an abundant and ubiquitous constituent of mammalian chromatin

Kurzanzeige
dc.contributor.authorWaldmann, Tanja
dc.contributor.authorScholten, Ingo
dc.contributor.authorKappes, Ferdinand
dc.contributor.authorHu, Hong Gang
dc.contributor.authorKnippers, Rolf
dc.date.accessioned2017-05-08T08:50:47Z
dc.date.available2017-05-08T08:50:47Z
dc.date.issued2004-12-08eng
dc.description.abstractThe protein DEK is an abundant and ubiquitous chromatin protein in multicellular organisms (not in yeast). It is expressed in more than a million copies/nucleus of rapidly proliferating mammalian cells. DEK has two DNA binding modules of which one includes a SAP box, a sequence motif that DEK shares with a number of other chromatin proteins. DEK has no apparent affinity to specific DNA sequences, but preferentially binds to superhelical and cruciform DNA, and induces positive supercoils into closed circular DNA. The available evidence strongly suggests that DEK could function as an architectural protein in chromatin comparable to the better known classic architectural chromatin proteins, the high-mobility group or HMG proteins.eng
dc.description.versionpublishedeng
dc.identifier.doi10.1016/j.gene.2004.08.029eng
dc.identifier.pmid15563827eng
dc.identifier.urihttps://kops.uni-konstanz.de/handle/123456789/38771
dc.language.isoengeng
dc.subject.ddc570eng
dc.titleThe DEK Protein : an abundant and ubiquitous constituent of mammalian chromatineng
dc.typeJOURNAL_ARTICLEeng
dspace.entity.typePublication
kops.citation.bibtex
@article{Waldmann2004-12-08Prote-38771,
  year={2004},
  doi={10.1016/j.gene.2004.08.029},
  title={The DEK Protein : an abundant and ubiquitous constituent of mammalian chromatin},
  number={1},
  volume={343},
  issn={0378-1119},
  journal={Gene},
  pages={1--9},
  author={Waldmann, Tanja and Scholten, Ingo and Kappes, Ferdinand and Hu, Hong Gang and Knippers, Rolf}
}
kops.citation.iso690WALDMANN, Tanja, Ingo SCHOLTEN, Ferdinand KAPPES, Hong Gang HU, Rolf KNIPPERS, 2004. The DEK Protein : an abundant and ubiquitous constituent of mammalian chromatin. In: Gene. 2004, 343(1), pp. 1-9. ISSN 0378-1119. eISSN 1879-0038. Available under: doi: 10.1016/j.gene.2004.08.029deu
kops.citation.iso690WALDMANN, Tanja, Ingo SCHOLTEN, Ferdinand KAPPES, Hong Gang HU, Rolf KNIPPERS, 2004. The DEK Protein : an abundant and ubiquitous constituent of mammalian chromatin. In: Gene. 2004, 343(1), pp. 1-9. ISSN 0378-1119. eISSN 1879-0038. Available under: doi: 10.1016/j.gene.2004.08.029eng
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kops.sourcefieldGene. 2004, <b>343</b>(1), pp. 1-9. ISSN 0378-1119. eISSN 1879-0038. Available under: doi: 10.1016/j.gene.2004.08.029deu
kops.sourcefield.plainGene. 2004, 343(1), pp. 1-9. ISSN 0378-1119. eISSN 1879-0038. Available under: doi: 10.1016/j.gene.2004.08.029deu
kops.sourcefield.plainGene. 2004, 343(1), pp. 1-9. ISSN 0378-1119. eISSN 1879-0038. Available under: doi: 10.1016/j.gene.2004.08.029eng
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