Publikation:

100 years after Liepmann : Lesion correlates of diminished selection and application of familiar versus novel tools

Lade...
Vorschaubild

Dateien

Stoll_2-1wtbieyd6q2f98.pdf
Stoll_2-1wtbieyd6q2f98.pdfGröße: 2.48 MBDownloads: 262

Datum

2022

Herausgeber:innen

Kontakt

ISSN der Zeitschrift

Electronic ISSN

ISBN

Bibliografische Daten

Verlag

Schriftenreihe

Auflagebezeichnung

ArXiv-ID

Internationale Patentnummer

Link zur Lizenz

Angaben zur Forschungsförderung

Projekt

Open Access-Veröffentlichung
Open Access Hybrid
Core Facility der Universität Konstanz

Gesperrt bis

Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

Cortex. Elsevier. 2022, 146, pp. 1-23. ISSN 0010-9452. eISSN 1973-8102. Available under: doi: 10.1016/j.cortex.2021.10.002

Zusammenfassung

100 years ago, Liepmann highlighted the role of left ventro-dorsal lesions for impairments in conceptual (rather ventral) and motor (more dorsal) related aspects of apraxia. Many studies thereafter attributed to an extended left fronto-temporo-parietal network. Yet, to date there are only few studies that looked at apraxic performance in the selection and application of familiar versus novel tools.

In the current study we applied modern voxel-based lesion-symptom mapping (VLSM) to analyze neural correlates of impaired selection and application of familiar versus novel tools. 58 left (LBD) and 51 right brain damaged (RBD) stroke patients participated in the Novel Tools Test (NTT) and the Familiar Tools Test (FTT) of the Diagnostic Instrument for Limb Apraxia (DILA-S). We further assessed performance in control tasks, namely semantic knowledge (BOSU), visuo-spatial working memory (Corsi Block Tapping) and meaningless imitation of gestures (IML).

Impaired tool use was most pronounced after LBD. Our VLSM results in the LBD-group suggested that selection versus application-related aspects of praxis and semantics of familiar versus novel tool use can be behaviorally and neuro-anatomically differentiated. For impairments in familiar tool tasks, the major focus of lesion maps was rather ventral while deficiencies in novel tool tasks went along with rather dorsal lesions. Affected selection processes were linked to rather anterior lesions, while impacted application processes went along with rather posterior lesion maps. In our study, particular tool selection processes were rather specific for familiar versus novel tools. Foci for lesion overlaps of experimental and control tasks were noticed ventrally for semantic knowledge and FTT, in fronto-parietal regions for working memory and NTT, and ventro-dorsally for imitation of meaningless gestures and the application of NTT and FTT.

We visualized our current interpretation within a neuroanatomical model for apraxia of tool use.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
150 Psychologie

Schlagwörter

apraxia, tool use, VLSM, neuroanatomical model, novel tools

Konferenz

Rezension
undefined / . - undefined, undefined

Forschungsvorhaben

Organisationseinheiten

Zeitschriftenheft

Zugehörige Datensätze in KOPS

Zitieren

ISO 690STOLL, Sarah, Lisa FINKEL, Ilka BUCHMANN, Thomas HASSA, Stefan SPITERI, Joachim LIEPERT, Jennifer RANDERATH, 2022. 100 years after Liepmann : Lesion correlates of diminished selection and application of familiar versus novel tools. In: Cortex. Elsevier. 2022, 146, pp. 1-23. ISSN 0010-9452. eISSN 1973-8102. Available under: doi: 10.1016/j.cortex.2021.10.002
BibTex
@article{Stoll2022-01years-55321,
  year={2022},
  doi={10.1016/j.cortex.2021.10.002},
  title={100 years after Liepmann : Lesion correlates of diminished selection and application of familiar versus novel tools},
  volume={146},
  issn={0010-9452},
  journal={Cortex},
  pages={1--23},
  author={Stoll, Sarah and Finkel, Lisa and Buchmann, Ilka and Hassa, Thomas and Spiteri, Stefan and Liepert, Joachim and Randerath, Jennifer}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/55321">
    <dcterms:title>100 years after Liepmann : Lesion correlates of diminished selection and application of familiar versus novel tools</dcterms:title>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dc:contributor>Buchmann, Ilka</dc:contributor>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2021-10-25T06:45:08Z</dc:date>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:contributor>Liepert, Joachim</dc:contributor>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/55321"/>
    <dc:creator>Liepert, Joachim</dc:creator>
    <dc:creator>Spiteri, Stefan</dc:creator>
    <dc:creator>Finkel, Lisa</dc:creator>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/55321/1/Stoll_2-1wtbieyd6q2f98.pdf"/>
    <dc:contributor>Randerath, Jennifer</dc:contributor>
    <dc:creator>Buchmann, Ilka</dc:creator>
    <dcterms:abstract xml:lang="eng">100 years ago, Liepmann highlighted the role of left ventro-dorsal lesions for impairments in conceptual (rather ventral) and motor (more dorsal) related aspects of apraxia. Many studies thereafter attributed to an extended left fronto-temporo-parietal network. Yet, to date there are only few studies that looked at apraxic performance in the selection and application of familiar versus novel tools.&lt;br /&gt;&lt;br /&gt;In the current study we applied modern voxel-based lesion-symptom mapping (VLSM) to analyze neural correlates of impaired selection and application of familiar versus novel tools. 58 left (LBD) and 51 right brain damaged (RBD) stroke patients participated in the Novel Tools Test (NTT) and the Familiar Tools Test (FTT) of the Diagnostic Instrument for Limb Apraxia (DILA-S). We further assessed performance in control tasks, namely semantic knowledge (BOSU), visuo-spatial working memory (Corsi Block Tapping) and meaningless imitation of gestures (IML).&lt;br /&gt;&lt;br /&gt;Impaired tool use was most pronounced after LBD. Our VLSM results in the LBD-group suggested that selection versus application-related aspects of praxis and semantics of familiar versus novel tool use can be behaviorally and neuro-anatomically differentiated. For impairments in familiar tool tasks, the major focus of lesion maps was rather ventral while deficiencies in novel tool tasks went along with rather dorsal lesions. Affected selection processes were linked to rather anterior lesions, while impacted application processes went along with rather posterior lesion maps. In our study, particular tool selection processes were rather specific for familiar versus novel tools. Foci for lesion overlaps of experimental and control tasks were noticed ventrally for semantic knowledge and FTT, in fronto-parietal regions for working memory and NTT, and ventro-dorsally for imitation of meaningless gestures and the application of NTT and FTT.&lt;br /&gt;&lt;br /&gt;We visualized our current interpretation within a neuroanatomical model for apraxia of tool use.</dcterms:abstract>
    <dc:contributor>Finkel, Lisa</dc:contributor>
    <dc:contributor>Spiteri, Stefan</dc:contributor>
    <dc:creator>Stoll, Sarah</dc:creator>
    <dc:contributor>Hassa, Thomas</dc:contributor>
    <dc:language>eng</dc:language>
    <dcterms:issued>2022-01</dcterms:issued>
    <dc:contributor>Stoll, Sarah</dc:contributor>
    <dc:creator>Randerath, Jennifer</dc:creator>
    <dc:creator>Hassa, Thomas</dc:creator>
    <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by/4.0/"/>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/55321/1/Stoll_2-1wtbieyd6q2f98.pdf"/>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2021-10-25T06:45:08Z</dcterms:available>
    <dc:rights>Attribution 4.0 International</dc:rights>
  </rdf:Description>
</rdf:RDF>

Interner Vermerk

xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter

Kontakt
URL der Originalveröffentl.

Prüfdatum der URL

Prüfungsdatum der Dissertation

Finanzierungsart

Kommentar zur Publikation

Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Ja
Diese Publikation teilen