Publikation: Structures of KOD and 9°N DNA Polymerases Complexed with Primer Template Duplex
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2013
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ChemBioChem. 2013, 14(9), pp. 1058-1062. ISSN 1439-4227. eISSN 1439-7633. Available under: doi: 10.1002/cbic.201300175
Zusammenfassung
Structures of KOD and 9°N DNA polymerases, two enzymes that are widely used to replicate DNA with highly modified nucleotides, were solved at high resolution in complex with primer/template duplex. The data elucidate substrate interaction of the two enzymes and pave the way for further optimisation of the enzymes and substrates.
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540 Chemie
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DNA replication, family B, modified nucleotide, polymerase chain reaction, X-ray structure
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BERGEN, Konrad, Karin BETZ, Wolfram WELTE, Kay DIEDERICHS, Andreas MARX, 2013. Structures of KOD and 9°N DNA Polymerases Complexed with Primer Template Duplex. In: ChemBioChem. 2013, 14(9), pp. 1058-1062. ISSN 1439-4227. eISSN 1439-7633. Available under: doi: 10.1002/cbic.201300175BibTex
@article{Bergen2013-06-17Struc-24010, year={2013}, doi={10.1002/cbic.201300175}, title={Structures of KOD and 9°N DNA Polymerases Complexed with Primer Template Duplex}, number={9}, volume={14}, issn={1439-4227}, journal={ChemBioChem}, pages={1058--1062}, author={Bergen, Konrad and Betz, Karin and Welte, Wolfram and Diederichs, Kay and Marx, Andreas} }
RDF
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