Publikation:

Comparative biological evaluation of two ethylene linked mixednext term binuclear ferrocene/ruthenium organometallic species

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12912.pdf
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2010

Autor:innen

Ott, Ingo
Kowalski, Konrad
Gust, Ronald
Maurer, Jörg

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http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-129121
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Open Access Green

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Chemie: Publikationen
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Published

Erschienen in

Bioorganic & Medicinal Chemistry Letters. 2010, 20(3), pp. 866-869. ISSN 0960-894X. eISSN 1464-3405

Zusammenfassung

Two ethylene linkednext term binuclear previous termmixednext term ferrocene/ruthenium complexes were biologically investigated in comparison to structurally related mononuclear ferrocene or ruthenium species with styryl substituents or ligands. Results indicated that the electron distribution (but not the redox potential), cellular uptake and (to some minor extent) anti-estrogenic effects were the key contributors to antiproliferative effects observed in tumor cell lines.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
540 Chemie

Schlagwörter

Bioorganometallic chemistry, Ferrocene, Ruthenium, Antitumor agents

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ISO 690OTT, Ingo, Konrad KOWALSKI, Ronald GUST, Jörg MAURER, Philipp MÜCKE, Rainer F. WINTER, 2010. Comparative biological evaluation of two ethylene linked mixednext term binuclear ferrocene/ruthenium organometallic species. In: Bioorganic & Medicinal Chemistry Letters. 2010, 20(3), pp. 866-869. ISSN 0960-894X. eISSN 1464-3405
BibTex
@article{Ott2010Compa-10022,
  year={2010},
  title={Comparative biological evaluation of two ethylene linked mixednext term binuclear ferrocene/ruthenium organometallic species},
  number={3},
  volume={20},
  issn={0960-894X},
  journal={Bioorganic & Medicinal Chemistry Letters},
  pages={866--869},
  author={Ott, Ingo and Kowalski, Konrad and Gust, Ronald and Maurer, Jörg and Mücke, Philipp and Winter, Rainer F.}
}
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