Publikation:

A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoprotein.

Lade...
Vorschaubild

Dateien

Zu diesem Dokument gibt es keine Dateien.

Datum

1993

Autor:innen

Ungewiss, Katharina
Azogui, Orly
Palacios, Ronald
Owen, Michael J.
Hayday, Adrian C.
Boehmer, Harald von

Herausgeber:innen

Kontakt

ISSN der Zeitschrift

Electronic ISSN

ISBN

Bibliografische Daten

Verlag

Schriftenreihe

Auflagebezeichnung

ArXiv-ID

Internationale Patentnummer

Angaben zur Forschungsförderung

Projekt

Open Access-Veröffentlichung
Core Facility der Universität Konstanz

Gesperrt bis

Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

Cell. 1993, 75(2), pp. 283-294. ISSN 0092-8674. Available under: doi: 10.1016/0092-8674(93)80070-U

Zusammenfassung

We describe a novel signal-transducing protein complex, which consists of the T cell receptor (TCR) β chain that is disulfide linked to a 33 kd glycoprotein and non-covalently associated with proteins of the CD3 complex on the surface of the pre-T cell line SCB.29. This 33 kd glycoprotein, provisionally designated gp33, represents neither of the known TCR chains and has escaped previous detection because it labels poorly by surface iodination. This glycoprotein is absent from the surface of mature T cell lines. A TCR β complex with identical molecular masses before and after reduction can be immunoprecipitated from surface-iodinated large thymocytes of TCR α-deficient mice. The novel gp33-TCR β complex may be entirely or partly responsible for control of early T cell development exerted by the TCR β protein.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
570 Biowissenschaften, Biologie

Schlagwörter

Konferenz

Rezension
undefined / . - undefined, undefined

Forschungsvorhaben

Organisationseinheiten

Zeitschriftenheft

Zugehörige Datensätze in KOPS

Zitieren

ISO 690GRÖTTRUP, Marcus, Katharina UNGEWISS, Orly AZOGUI, Ronald PALACIOS, Michael J. OWEN, Adrian C. HAYDAY, Harald von BOEHMER, 1993. A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoprotein.. In: Cell. 1993, 75(2), pp. 283-294. ISSN 0092-8674. Available under: doi: 10.1016/0092-8674(93)80070-U
BibTex
@article{Grottrup1993novel-16676,
  year={1993},
  doi={10.1016/0092-8674(93)80070-U},
  title={A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoprotein.},
  number={2},
  volume={75},
  issn={0092-8674},
  journal={Cell},
  pages={283--294},
  author={Gröttrup, Marcus and Ungewiss, Katharina and Azogui, Orly and Palacios, Ronald and Owen, Michael J. and Hayday, Adrian C. and Boehmer, Harald von}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/16676">
    <dc:contributor>Palacios, Ronald</dc:contributor>
    <dcterms:issued>1993</dcterms:issued>
    <dc:rights>terms-of-use</dc:rights>
    <dc:creator>Palacios, Ronald</dc:creator>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:contributor>Hayday, Adrian C.</dc:contributor>
    <dcterms:bibliographicCitation>Publ. in: Cell ; 75 (1993), 2. - S. 283-294</dcterms:bibliographicCitation>
    <dcterms:abstract xml:lang="eng">We describe a novel signal-transducing protein complex, which consists of the T cell receptor (TCR) β chain that is disulfide linked to a 33 kd glycoprotein and non-covalently associated with proteins of the CD3 complex on the surface of the pre-T cell line SCB.29. This 33 kd glycoprotein, provisionally designated gp33, represents neither of the known TCR chains and has escaped previous detection because it labels poorly by surface iodination. This glycoprotein is absent from the surface of mature T cell lines. A TCR β complex with identical molecular masses before and after reduction can be immunoprecipitated from surface-iodinated large thymocytes of TCR α-deficient mice. The novel gp33-TCR β complex may be entirely or partly responsible for control of early T cell development exerted by the TCR β protein.</dcterms:abstract>
    <dc:contributor>Gröttrup, Marcus</dc:contributor>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-11-16T06:28:50Z</dc:date>
    <dc:creator>Hayday, Adrian C.</dc:creator>
    <dc:contributor>Ungewiss, Katharina</dc:contributor>
    <dc:creator>Azogui, Orly</dc:creator>
    <dc:language>eng</dc:language>
    <dc:contributor>Boehmer, Harald von</dc:contributor>
    <dc:creator>Ungewiss, Katharina</dc:creator>
    <dc:creator>Boehmer, Harald von</dc:creator>
    <dc:contributor>Azogui, Orly</dc:contributor>
    <dc:contributor>Owen, Michael J.</dc:contributor>
    <dc:creator>Gröttrup, Marcus</dc:creator>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/16676"/>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <dcterms:title>A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoprotein.</dcterms:title>
    <dc:creator>Owen, Michael J.</dc:creator>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-11-16T06:28:50Z</dcterms:available>
  </rdf:Description>
</rdf:RDF>

Interner Vermerk

xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter

Kontakt
URL der Originalveröffentl.

Prüfdatum der URL

Prüfungsdatum der Dissertation

Finanzierungsart

Kommentar zur Publikation

Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Nein
Begutachtet
Diese Publikation teilen