Publikation: Comparison of metabolic pathways using constraint graph drawing
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Databases contain a large amount of data about metabolic pathways, in particular about similar pathways in different species. Biologists are familiar with visual representations of metabolic pathways. Visualizations help them to understand the complex relationships between the components of the pathways, to extract information from the data, and to compare pathways between different species. However, visual interfaces to metabolic pathway databases cannot cope well with the visual comparison of similar pathways in different species. This paper presents a new approach for the visual comparison of metabolic pathways using a constraint graph drawing algorithm. Using layout constraints the same parts of similar pathways in different species are placed side by side, thereby highlighting similarities and differences between these pathways. This visualization method can be used as a visual interface to databases and has been tested with data obtained from the BioPath system and from the KEGG database.
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SCHREIBER, Falk, 2003. Comparison of metabolic pathways using constraint graph drawing. APBC '03 : First Asia-Pacific bioinformatics conference on Bioinformatics 2003. Adelaide, Australia, 4. Feb. 2003 - 7. Feb. 2003. In: CHEN, Yi-Ping Phoebe, ed.. Bioinformatics 2003 : proceedings of the First Asia-Pacific Bioinformatics Conference, Adelaide, Australia, February 2003. Sydney: Australian Computer Society, 2003, pp. 105-110. Conferences in research and practice in information technology. 19. ISSN 1445-1336. ISBN 0-909925-97-6BibTex
@inproceedings{Schreiber2003Compa-40746, year={2003}, title={Comparison of metabolic pathways using constraint graph drawing}, url={https://dl.acm.org/citation.cfm?id=820203}, number={19}, isbn={0-909925-97-6}, issn={1445-1336}, publisher={Australian Computer Society}, address={Sydney}, series={Conferences in research and practice in information technology}, booktitle={Bioinformatics 2003 : proceedings of the First Asia-Pacific Bioinformatics Conference, Adelaide, Australia, February 2003}, pages={105--110}, editor={Chen, Yi-Ping Phoebe}, author={Schreiber, Falk} }
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