Publikation: Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons
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2002
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Behavioural Brain Research. 2002, 136(1), pp. 171-177. ISSN 0166-4328. Available under: doi: 10.1016/S0166-4328(02)00109-2
Zusammenfassung
Upon systemic administration of apomorphine, a potent dopamine agonist, pigeons show a bout of pecking behaviour. When the drug is repeatedly administered a sensitization takes place that is associated with pronounced discrimination learning. Here we show that intra-cerebral injections of apomorphine in the periphery of the nucleus accumbens of pigeons also elicit pecking. We additionally show that injections of 5-amino-phosphonohepatnoic acid, a NMDA-glutamate receptor blocker, into the Acc impairs the performance of a learned visual discrimination incorporating pecking as a choice response. We conclude that, as it is the case in mammals, the control mechanisms of learned sensory-motor behaviour in birds involves dopaminergic and glutamatergic synaptic transmission within the nucleus accumbens area.
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Fachgebiet (DDC)
150 Psychologie
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Pigeon, nucleus accumbens, pecking response, learned discrimination, glutamate antagonists, dopamine agonist, schizophrenia
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ACERBO, Martı́n J., Pascual A. GARGIULO, Ines KRUG, Juan DELIUS, 2002. Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons. In: Behavioural Brain Research. 2002, 136(1), pp. 171-177. ISSN 0166-4328. Available under: doi: 10.1016/S0166-4328(02)00109-2BibTex
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title={Behavioural consequences of nucleus accumbens dopaminergic stimulation and glutamatergic blocking in pigeons},
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volume={136},
issn={0166-4328},
journal={Behavioural Brain Research},
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