Publikation:

Evidence for In Vivo High-Frequency Periodicity of Plasma Beta-Endorphin in Humans

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1995

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Imthurn, Bruno
Rosselli, Marinella
Keller, Paul J.

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Hormone and Metabolic Research. 1995, 27(04), pp. 189-193. ISSN 0018-5043. eISSN 1439-4286. Available under: doi: 10.1055/s-2007-979937

Zusammenfassung

Objective
To investigate whether high-frequency periodic fluctuation in the release of plasma immunoreactive (ir)-beta-endorphin occurs in humans. Design, patients and measurements: Blood was collected at 90-sec intervals for 1 hour from the forearm vein of four healthy women and subsequently analysed for ir-beta-endorphin by radioimmunoassay.

Results
In all women circulating beta-endorphin release followed a high-frequency periodic rhythm pattern. The estimated spectral densities within the four subjects varied between 3.6 min to 4.9 min.

Conclusions
Our results provide the first in vivo evidence that fluctuations in the release of beta-endorphin in humans cannot only be characterized by low-frequency pulses, but also by a high frequency periodic rhythm.

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610 Medizin

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ISO 690IMTHURN, Bruno, Marinella ROSSELLI, Jan BERAN, Paul J. KELLER, 1995. Evidence for In Vivo High-Frequency Periodicity of Plasma Beta-Endorphin in Humans. In: Hormone and Metabolic Research. 1995, 27(04), pp. 189-193. ISSN 0018-5043. eISSN 1439-4286. Available under: doi: 10.1055/s-2007-979937
BibTex
@article{Imthurn1995-04Evide-27481,
  year={1995},
  doi={10.1055/s-2007-979937},
  title={Evidence for In Vivo High-Frequency Periodicity of Plasma Beta-Endorphin in Humans},
  number={04},
  volume={27},
  issn={0018-5043},
  journal={Hormone and Metabolic Research},
  pages={189--193},
  author={Imthurn, Bruno and Rosselli, Marinella and Beran, Jan and Keller, Paul J.}
}
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