Publikation: Fast PCA for processing Calcium-imaging data from the brain of Drosophila melanogaster
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2011
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Published
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Proceedings of the ACM fifth international workshop on Data and text mining in biomedical informatics - DTMBIO '11. New York, New York, USA: ACM Press, 2011, pp. 3-10. ISBN 978-1-4503-0960-8. Available under: doi: 10.1145/2064696.2064700
Zusammenfassung
The calcium-imaging technique allows us to record movies of brain activity in the antennal lobe of the fruitfly Drosophila melanogaster, a brain compartment where information about odors is processed. For signal processing that scales up with the growing data sizes in imaging, we have developed an approximate Principal Component Analysis (PCA) for fast dimensionality reduction. The approach relies on selecting a set of relevant pixels from the movies based on a priori knowledge about the nature of the data, ensuring a highquality approximation. Once in PCA space, we can efficiently perform source separation, e.g to detect biological signals in the movies and to remove artifacts.
Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
570 Biowissenschaften, Biologie
Schlagwörter
Biological image mining, approximate PCA, Monte Carlo algorithm, source separation
Konferenz
The ACM fifth international workshop on Data and text mining in biomedical informatics - DTMBIO '11, 24. Okt. 2011 - 24. Okt. 2011, Glasgow, Scotland, UK
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STRAUCH, Martin, C. Giovanni GALIZIA, 2011. Fast PCA for processing Calcium-imaging data from the brain of Drosophila melanogaster. The ACM fifth international workshop on Data and text mining in biomedical informatics - DTMBIO '11. Glasgow, Scotland, UK, 24. Okt. 2011 - 24. Okt. 2011. In: Proceedings of the ACM fifth international workshop on Data and text mining in biomedical informatics - DTMBIO '11. New York, New York, USA: ACM Press, 2011, pp. 3-10. ISBN 978-1-4503-0960-8. Available under: doi: 10.1145/2064696.2064700BibTex
@inproceedings{Strauch2011proce-17736,
year={2011},
doi={10.1145/2064696.2064700},
title={Fast PCA for processing Calcium-imaging data from the brain of Drosophila melanogaster},
isbn={978-1-4503-0960-8},
publisher={ACM Press},
address={New York, New York, USA},
booktitle={Proceedings of the ACM fifth international workshop on Data and text mining in biomedical informatics - DTMBIO '11},
pages={3--10},
author={Strauch, Martin and Galizia, C. Giovanni}
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