Publikation: Molecular Insights into Error-Prone DNA Replication and Error-Free Lesion Bypass
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2002
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ChemBioChem. 2002, 3(5), pp. 405-407. ISSN 1439-4227. eISSN 1439-7633. Available under: doi: 10.1002/1439-7633(20020503)3:5<405::AID-CBIC405>3.0.CO;2-4
Zusammenfassung
New DNA polymerase structures that differ significantly from known high-fidelity DNA polymerases provide new insights into how polymerases bypass damaged DNA like 1. Crystal structures of several Y-family DNA polymerases have recently been solved (see right-hand picture) and suggest that more open active sites may be the reason for the error propensity of low-fidelity polymerases.
Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
540 Chemie
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DNA damage, DNA polymerases, DNA replication, thymidine dimers, UV light
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MARX, Andreas, Daniel SUMMERER, 2002. Molecular Insights into Error-Prone DNA Replication and Error-Free Lesion Bypass. In: ChemBioChem. 2002, 3(5), pp. 405-407. ISSN 1439-4227. eISSN 1439-7633. Available under: doi: 10.1002/1439-7633(20020503)3:5<405::AID-CBIC405>3.0.CO;2-4BibTex
@article{Marx2002Molec-9607,
year={2002},
doi={10.1002/1439-7633(20020503)3:5<405::AID-CBIC405>3.0.CO;2-4},
title={Molecular Insights into Error-Prone DNA Replication and Error-Free Lesion Bypass},
number={5},
volume={3},
issn={1439-4227},
journal={ChemBioChem},
pages={405--407},
author={Marx, Andreas and Summerer, Daniel}
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