Publikation: Synthesis of 4′-C-Acylated Thymidines
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1996
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Erdmann, Peter
Senn, Martin
Körner, Steffi
Jungo, Tobias
Petretta, Mario
Imwinkelried, Petra
Dussy, Adrian
Kulicke, Klaus J.
Macko, Ludwig
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Helvetica Chimica Acta. 1996, 79(7), pp. 1980-1994. ISSN 0018-019X. eISSN 1522-2675. Available under: doi: 10.1002/hlca.19960790720
Zusammenfassung
Two synthetic pathways towards 4′-C-acylthymidines are presented. These modified mononucleosides are precursors of the 2′-deoxyribonucleotide 4′-C-radical. They were converted into their corresponding 3′-O-[(2-cyanoethyl) N,N-diisopropylphosphoramidites] 3a–c and incorporated in oligonucleotides by solid-phase synthesis. The structure of some modified nucleosides was revealed by X-ray crystal-structure analysis.
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MARX, Andreas, Peter ERDMANN, Martin SENN, Steffi KÖRNER, Tobias JUNGO, Mario PETRETTA, Petra IMWINKELRIED, Adrian DUSSY, Klaus J. KULICKE, Ludwig MACKO, Margareta ZEHNDER, Bernd GIESE, 1996. Synthesis of 4′-C-Acylated Thymidines. In: Helvetica Chimica Acta. 1996, 79(7), pp. 1980-1994. ISSN 0018-019X. eISSN 1522-2675. Available under: doi: 10.1002/hlca.19960790720BibTex
@article{Marx1996Synth-34107, year={1996}, doi={10.1002/hlca.19960790720}, title={Synthesis of 4′-C-Acylated Thymidines}, number={7}, volume={79}, issn={0018-019X}, journal={Helvetica Chimica Acta}, pages={1980--1994}, author={Marx, Andreas and Erdmann, Peter and Senn, Martin and Körner, Steffi and Jungo, Tobias and Petretta, Mario and Imwinkelried, Petra and Dussy, Adrian and Kulicke, Klaus J. and Macko, Ludwig and Zehnder, Margareta and Giese, Bernd} }
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