Publikation:

Efficient Suppression of Gene Expression by targeting 5'-UTR-based RNA Quadruplexes with Bisquinolinium Compounds

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2011

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Halder, Kangkan
Largy, Eric
Benzler, Martin
Teulade-Fichou, Marie-Paule

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ChemBioChem. 2011, 12(11), pp. 1663-1668. ISSN 1439-4227. eISSN 1439-7633. Available under: doi: 10.1002/cbic.201100228

Zusammenfassung

Fourth amendment: RNA quadruplexes located in the 5′-untranslated regions (5′-UTR in the figure) of mRNAs inhibit gene expression. This effect can be amplified by targeting RNA quadruplexes with specific bisquinolinium compounds.

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Fachgebiet (DDC)
540 Chemie

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gene expression, nucleic acids, quinoline, RNA quadruplexes

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ISO 690HALDER, Kangkan, Eric LARGY, Martin BENZLER, Marie-Paule TEULADE-FICHOU, Jörg S. HARTIG, 2011. Efficient Suppression of Gene Expression by targeting 5'-UTR-based RNA Quadruplexes with Bisquinolinium Compounds. In: ChemBioChem. 2011, 12(11), pp. 1663-1668. ISSN 1439-4227. eISSN 1439-7633. Available under: doi: 10.1002/cbic.201100228
BibTex
@article{Halder2011-07-25Effic-15678,
  year={2011},
  doi={10.1002/cbic.201100228},
  title={Efficient Suppression of Gene Expression by targeting 5'-UTR-based RNA Quadruplexes with Bisquinolinium Compounds},
  number={11},
  volume={12},
  issn={1439-4227},
  journal={ChemBioChem},
  pages={1663--1668},
  author={Halder, Kangkan and Largy, Eric and Benzler, Martin and Teulade-Fichou, Marie-Paule and Hartig, Jörg S.}
}
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