Publikation: Synthesis of 4′-C-alkylated-5-iodo-2′-deoxypyrimidine nucleosides
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2013
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Published
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Arkivoc. 2013(2), pp. 46-59. ISSN 1551-7004. eISSN 1551-7012
Zusammenfassung
Starting from available ribose-building blocks, the 4′-C-methyl-, 4′-C-ethyl- and the new 4′-Cpropyl-substituted deoxyuridines were synthesized. Afterwards we converted 4′-C-alkylated-2′- deoxyuridines into the corresponding 4′-C-alkylated-5-iodo-2′-deoxyuridines 3a-c and those in turn into the 4′-C-alkylated-5-iodo-2′-deoxycytidines 4a-c.
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540 Chemie
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DNA replication, nucleoside analogues, 4′-C-alkylation, antiviral agents, carbohydrate, halogenation
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STRITTMATTER, Tobias, Joos ASCHENBRENNER, Normann HARDT, Andreas MARX, 2013. Synthesis of 4′-C-alkylated-5-iodo-2′-deoxypyrimidine nucleosides. In: Arkivoc. 2013(2), pp. 46-59. ISSN 1551-7004. eISSN 1551-7012BibTex
@article{Strittmatter2013Synth-20665,
year={2013},
title={Synthesis of 4′-C-alkylated-5-iodo-2′-deoxypyrimidine nucleosides},
number={2},
issn={1551-7004},
journal={Arkivoc},
pages={46--59},
author={Strittmatter, Tobias and Aschenbrenner, Joos and Hardt, Normann and Marx, Andreas}
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