Titanocene Difluorides with Improved Cytotoxic Activity

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16_Inorg.Chem.2010.pdf
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2010
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Claffey, James
Müller-Bunz, Helge
Tacke, Matthias
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Titanocene difluorides can be obtained by halide metathesis of the respective titanocene dichlorides with trimethyltin fluoride (Me3SnF), giving access to a new class of cytotoxic active substances. Furthermore, an improved method for the synthesis of diaryl-substituted titanocene dichlorides is presented.

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ISO 690EGER, Silvia, Timo IMMEL, James CLAFFEY, Helge MÜLLER-BUNZ, Matthias TACKE, Ulrich GROTH, Thomas HUHN, 2010. Titanocene Difluorides with Improved Cytotoxic Activity. In: Inorganic Chemistry. 2010, 49(4), pp. 1292-1294. ISSN 0020-1669. eISSN 1520-510X. Available under: doi: 10.1021/ic9022163
BibTex
@article{Eger2010Titan-12588,
  year={2010},
  doi={10.1021/ic9022163},
  title={Titanocene Difluorides with Improved Cytotoxic Activity},
  number={4},
  volume={49},
  issn={0020-1669},
  journal={Inorganic Chemistry},
  pages={1292--1294},
  author={Eger, Silvia and Immel, Timo and Claffey, James and Müller-Bunz, Helge and Tacke, Matthias and Groth, Ulrich and Huhn, Thomas}
}
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