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Nutrition and the ageing brain : Moving towards clinical applications

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Datum

2020

Autor:innen

Flanagan, Emma
Lamport, Daniel
Brennan, Lorraine
Burnet, Philip
Calabrese, Vittorio
Cunnane, Stephen C.
de Wilde, Martijn C.
Dye, Louise
Vauzour, David
et al.

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Open Access-Veröffentlichung
Open Access Hybrid
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Published

Erschienen in

Ageing Research Reviews. Elsevier. 2020, 62, 101079. ISSN 1568-1637. eISSN 1872-9649. Available under: doi: 10.1016/j.arr.2020.101079

Zusammenfassung

The global increases in life expectancy and population have resulted in a growing ageing population and with it a growing number of people living with age-related neurodegenerative conditions and dementia, shifting focus towards methods of prevention, with lifestyle approaches such as nutrition representing a promising avenue for further development. This overview summarises the main themes discussed during the 3rd Symposium on "Nutrition for the Ageing Brain: Moving Towards Clinical Applications" held in Madrid in August 2018, enlarged with the current state of knowledge on how nutrition influences healthy ageing and gives recommendations regarding how the critical field of nutrition and neurodegeneration research should move forward into the future. Specific nutrients are discussed as well as the impact of multi-nutrient and whole diet approaches, showing particular promise to combatting the growing burden of age-related cognitive decline. The emergence of new avenues for exploring the role of diet in healthy ageing, such as the impact of the gut microbiome and development of new techniques (imaging measures of brain metabolism, metabolomics, biomarkers) are enabling researchers to approach finding answers to these questions. But the translation of these findings into clinical and public health contexts remains an obstacle due to significant shortcomings in nutrition research or pressure on the scientific community to communicate recommendations to the general public in a convincing and accessible way. Some promising programs exist but further investigation to improve our understanding of the mechanisms by which nutrition can improve brain health across the human lifespan is still required.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
570 Biowissenschaften, Biologie

Schlagwörter

Brain, Healthy ageing, Preventative diet, Microbiota, Neuroprotection, Cognitive ageing

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ISO 690FLANAGAN, Emma, Daniel LAMPORT, Lorraine BRENNAN, Philip BURNET, Vittorio CALABRESE, Stephen C. CUNNANE, Martijn C. DE WILDE, Louise DYE, Thomas HARTUNG, David VAUZOUR, 2020. Nutrition and the ageing brain : Moving towards clinical applications. In: Ageing Research Reviews. Elsevier. 2020, 62, 101079. ISSN 1568-1637. eISSN 1872-9649. Available under: doi: 10.1016/j.arr.2020.101079
BibTex
@article{Flanagan2020-09Nutri-51116,
  year={2020},
  doi={10.1016/j.arr.2020.101079},
  title={Nutrition and the ageing brain : Moving towards clinical applications},
  volume={62},
  issn={1568-1637},
  journal={Ageing Research Reviews},
  author={Flanagan, Emma and Lamport, Daniel and Brennan, Lorraine and Burnet, Philip and Calabrese, Vittorio and Cunnane, Stephen C. and de Wilde, Martijn C. and Dye, Louise and Hartung, Thomas and Vauzour, David},
  note={Article Number: 101079}
}
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