Publikation: Control of death receptor ligand activity by posttranslational modifications
Lade...
Dateien
Datum
2010
Autor:innen
Herausgeber:innen
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Springer
Schriftenreihe
Auflagebezeichnung
URI (zitierfähiger Link)
DOI (zitierfähiger Link)
Internationale Patentnummer
Link zur Lizenz
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Open Access Green
Sammlungen
Core Facility der Universität Konstanz
Titel in einer weiteren Sprache
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published
Erschienen in
Cellular and Molecular Life Sciences. 2010, 67(10), pp. 1631-1642. ISSN 1420-682X. eISSN 1420-9071. Available under: doi: 10.1007/s00018-010-0289-7
Zusammenfassung
The death receptor ligands are involved in many physiological and pathological processes involving triggering of apoptosis, inflammation, proliferation, and activation. The expression of these molecules is reported to be tightly regulated at the transcriptional level. However, over the last few years, an increasing number of data demonstrated that the control of transcription is only one of the mechanisms that manage the expression of the death receptor ligands. Thus, this review is focused on posttranslational regulation of the three main members of this family, namely FasL, TNF-α, and TRAIL. We discuss here the importance of distribution, storage, and degranulation of these molecules, as well as their shedding by proteases on the control of death receptor ligands expression and activity.
Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
570 Biowissenschaften, Biologie
Schlagwörter
FasL, TNF, TRAIL, Rafts, Lysosomes, Degranulation, ADAM, Metalloprotease, Shedding
Konferenz
Rezension
undefined / . - undefined, undefined
Zitieren
ISO 690
WEINLICH, Ricardo, Thomas BRUNNER, Gustavo P. AMARANTE-MENDES, 2010. Control of death receptor ligand activity by posttranslational modifications. Springer. In: Cellular and Molecular Life Sciences. 2010, 67(10), pp. 1631-1642. ISSN 1420-682X. eISSN 1420-9071. Available under: doi: 10.1007/s00018-010-0289-7BibTex
@article{Weinlich2010Contr-13537,
year={2010},
doi={10.1007/s00018-010-0289-7},
title={Control of death receptor ligand activity by posttranslational modifications},
number={10},
volume={67},
issn={1420-682X},
journal={Cellular and Molecular Life Sciences},
pages={1631--1642},
author={Weinlich, Ricardo and Brunner, Thomas and Amarante-Mendes, Gustavo P.}
}RDF
<rdf:RDF
xmlns:dcterms="http://purl.org/dc/terms/"
xmlns:dc="http://purl.org/dc/elements/1.1/"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:bibo="http://purl.org/ontology/bibo/"
xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
xmlns:foaf="http://xmlns.com/foaf/0.1/"
xmlns:void="http://rdfs.org/ns/void#"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#" >
<rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/13537">
<dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
<dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-05-30T08:25:20Z</dc:date>
<dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
<dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/13537/1/2010_Control_of_death_Weinlich.pdf"/>
<dc:publisher>Springer</dc:publisher>
<dcterms:issued>2010</dcterms:issued>
<bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/13537"/>
<dc:creator>Amarante-Mendes, Gustavo P.</dc:creator>
<dc:contributor>Brunner, Thomas</dc:contributor>
<dc:creator>Weinlich, Ricardo</dc:creator>
<dcterms:bibliographicCitation>First publ. in: Cellular and Molecular Life Sciences ; 67 (2010), 10. - pp. 1631-1642</dcterms:bibliographicCitation>
<dcterms:title>Control of death receptor ligand activity by posttranslational modifications</dcterms:title>
<dc:contributor>Amarante-Mendes, Gustavo P.</dc:contributor>
<dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
<dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/13537/1/2010_Control_of_death_Weinlich.pdf"/>
<dc:contributor>Weinlich, Ricardo</dc:contributor>
<dcterms:abstract xml:lang="eng">The death receptor ligands are involved in many physiological and pathological processes involving triggering of apoptosis, inflammation, proliferation, and activation. The expression of these molecules is reported to be tightly regulated at the transcriptional level. However, over the last few years, an increasing number of data demonstrated that the control of transcription is only one of the mechanisms that manage the expression of the death receptor ligands. Thus, this review is focused on posttranslational regulation of the three main members of this family, namely FasL, TNF-α, and TRAIL. We discuss here the importance of distribution, storage, and degranulation of these molecules, as well as their shedding by proteases on the control of death receptor ligands expression and activity.</dcterms:abstract>
<void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
<dc:rights>terms-of-use</dc:rights>
<foaf:homepage rdf:resource="http://localhost:8080/"/>
<dc:creator>Brunner, Thomas</dc:creator>
<dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-05-30T08:25:20Z</dcterms:available>
<dc:language>eng</dc:language>
</rdf:Description>
</rdf:RDF>Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
