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Cognitive-behavioral therapy for patients with post-COVID-19 condition (CBT-PCC) : a feasibility trial

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2024

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Huth, Daniel
Bräscher, Anne-Kathrin
Birke, Gunnar
Herrmann, Christoph
Witthöft, Michael

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Psychological Medicine. Cambridge University Press (CUP). 2024, 54(6), S. 1122-1132. ISSN 0033-2917. eISSN 1469-8978. Verfügbar unter: doi: 10.1017/s0033291723002921

Zusammenfassung

Background: The post-COVID-19 condition describes the persistence or onset of somatic symptoms (e.g. fatigue) after acute COVID-19. Based on an existing cognitive-behavioral treatment protocol, we developed a specialized group intervention for individuals with post-COVID-19 condition. The present study examines the feasibility, acceptance, and effectiveness of the program for inpatients in a neurological rehabilitation setting.

Methods: The treatment program comprises eight sessions and includes psychoeducational and experience-based interventions on common psychophysiological mechanisms of persistent somatic symptoms. A feasibility trial was conducted using a one-group design in a naturalistic setting. N = 64 inpatients with a history of mild COVID-19 that fulfilled WHO criteria for post-COVID-19 condition were enrolled. After each session, evaluation forms were completed and psychometric questionnaires on somatic and psychopathological symptom burden were collected pre- and post-intervention.

Results: The treatment program was well received by participants and therapists. Each session was rated as comprehensible and overall satisfaction with the sessions was high. Pre-post effect sizes (of standard rehabilitation incl. new treatment program; intention-to-treat) showed significantly reduced subjective fatigue (p < 0.05, dav = 0.33) and improved disease coping (ps < 0.05, dav = 0.33–0.49).

Conclusions: Our results support the feasibility and acceptance of the newly developed cognitive-behavioral group intervention for individuals with post-COVID-19 condition. Yet, findings have to be interpreted cautiously due to the lack of a control group and follow-up measurement, the small sample size, and a relatively high drop-out rate.

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ISO 690HUTH, Daniel, Anne-Kathrin BRÄSCHER, Sarah THOLL, Johanna FIESS, Gunnar BIRKE, Christoph HERRMANN, Michael JÖBGES, Daniela MIER, Michael WITTHÖFT, 2024. Cognitive-behavioral therapy for patients with post-COVID-19 condition (CBT-PCC) : a feasibility trial. In: Psychological Medicine. Cambridge University Press (CUP). 2024, 54(6), S. 1122-1132. ISSN 0033-2917. eISSN 1469-8978. Verfügbar unter: doi: 10.1017/s0033291723002921
BibTex
@article{Huth2024-04Cogni-68028,
  year={2024},
  doi={10.1017/s0033291723002921},
  title={Cognitive-behavioral therapy for patients with post-COVID-19 condition (CBT-PCC) : a feasibility trial},
  number={6},
  volume={54},
  issn={0033-2917},
  journal={Psychological Medicine},
  pages={1122--1132},
  author={Huth, Daniel and Bräscher, Anne-Kathrin and Tholl, Sarah and Fiess, Johanna and Birke, Gunnar and Herrmann, Christoph and Jöbges, Michael and Mier, Daniela and Witthöft, Michael}
}
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The post-COVID-19 condition describes the persistence or onset of somatic symptoms (e.g. fatigue) after acute COVID-19. Based on an existing cognitive-behavioral treatment protocol, we developed a specialized group intervention for individuals with post-COVID-19 condition. The present study examines the feasibility, acceptance, and effectiveness of the program for inpatients in a neurological rehabilitation setting.

Methods: The treatment program comprises eight sessions and includes psychoeducational and experience-based interventions on common psychophysiological mechanisms of persistent somatic symptoms. A feasibility trial was conducted using a one-group design in a naturalistic setting. N = 64 inpatients with a history of mild COVID-19 that fulfilled WHO criteria for post-COVID-19 condition were enrolled. After each session, evaluation forms were completed and psychometric questionnaires on somatic and psychopathological symptom burden were collected pre- and post-intervention.

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