Publikation: Spreading of bio-adhesive vesicles on DNA carpets
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2008
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Soft Matter. 2008, 4, pp. 828-832. Available under: doi: 10.1039/B715530A
Zusammenfassung
Cell-adhesion events involve often the formation of a contact region between phospholipid membranes decorated with a variety of bio-macromolecular species. We mimic here such hairy bio-adhesive contact zones by spreading phospholipid vesicles onto surfaces carpeted with end-grafted l-phage DNA. Our study reveals that the spreading front acts as a scraper that strongly stretches the DNA molecules, and that the multiple bonds created during vesicle spreading effectively staple the stretched chains in the gap between the membrane and the substrate. The scraping and stapling mechanisms revealed here for the long DNA molecules are expected to also play a role in actual bio-adhesion events of cell walls and tissues.
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530 Physik
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HISETTE, Marie-Laure, Paula HADDAD, Thomas GISLER, Carlos Manuel MARQUES, André Pierre SCHRÖDER, 2008. Spreading of bio-adhesive vesicles on DNA carpets. In: Soft Matter. 2008, 4, pp. 828-832. Available under: doi: 10.1039/B715530ABibTex
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year={2008},
doi={10.1039/B715530A},
title={Spreading of bio-adhesive vesicles on DNA carpets},
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journal={Soft Matter},
pages={828--832},
author={Hisette, Marie-Laure and Haddad, Paula and Gisler, Thomas and Marques, Carlos Manuel and Schröder, André Pierre}
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