Publikation: Do H+ ions obscure electrogenic Na+ and K+ binding in the E1 state of the Na,K-ATPase?
Lade...
Dateien
Datum
2002
Autor:innen
Diller, Anna
Herausgeber:innen
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
URI (zitierfähiger Link)
DOI (zitierfähiger Link)
Internationale Patentnummer
Link zur Lizenz
Angaben zur Forschungsförderung
Projekt
Open Access-Veröffentlichung
Open Access Green
Sammlungen
Core Facility der Universität Konstanz
Titel in einer weiteren Sprache
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published
Erschienen in
FEBS Letters. 2002, 532(1-2), pp. 198-202. ISSN 0014-5793. Available under: doi: 10.1016/S0014-5793(02)03675-X
Zusammenfassung
In contrast to other P-type ATPases, the Na,K-ATPase binding and release of ions on the cytoplasmic side, to the state called E1, is not electrogenic with the exception of the third Na+. Since the high-resolution structure of the closely related SR Ca-ATPase in state E1 revealed the ion-binding sites deep inside the transmembrane part of the protein, the missing electrogenicity in state E1 can be explained by an obscuring counter-movement of H+ ions. Evidence for such a mechanism is presented by analysis of pH effects of Na+ and K+ binding and by electrogenic H+ movements in the E1 conformation of the Na,K-ATPase.
Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
570 Biowissenschaften, Biologie
Schlagwörter
Active ion transport, Sodium mump, Binding sites, electrogenicity, Competition
Konferenz
Rezension
undefined / . - undefined, undefined
Zitieren
ISO 690
APELL, Hans-Jürgen, Anna DILLER, 2002. Do H+ ions obscure electrogenic Na+ and K+ binding in the E1 state of the Na,K-ATPase?. In: FEBS Letters. 2002, 532(1-2), pp. 198-202. ISSN 0014-5793. Available under: doi: 10.1016/S0014-5793(02)03675-XBibTex
@article{Apell2002obscu-7883,
year={2002},
doi={10.1016/S0014-5793(02)03675-X},
title={Do H+ ions obscure electrogenic Na+ and K+ binding in the E1 state of the Na,K-ATPase?},
number={1-2},
volume={532},
issn={0014-5793},
journal={FEBS Letters},
pages={198--202},
author={Apell, Hans-Jürgen and Diller, Anna}
}RDF
<rdf:RDF
xmlns:dcterms="http://purl.org/dc/terms/"
xmlns:dc="http://purl.org/dc/elements/1.1/"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:bibo="http://purl.org/ontology/bibo/"
xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
xmlns:foaf="http://xmlns.com/foaf/0.1/"
xmlns:void="http://rdfs.org/ns/void#"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#" >
<rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/7883">
<dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
<dc:rights>Attribution-NonCommercial-NoDerivs 2.0 Generic</dc:rights>
<dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:38:15Z</dc:date>
<dc:format>application/pdf</dc:format>
<dcterms:issued>2002</dcterms:issued>
<dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-03-24T17:38:15Z</dcterms:available>
<dcterms:rights rdf:resource="http://creativecommons.org/licenses/by-nc-nd/2.0/"/>
<dc:creator>Apell, Hans-Jürgen</dc:creator>
<dc:creator>Diller, Anna</dc:creator>
<dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/7883/1/Do_H_ions_obscure.pdf"/>
<foaf:homepage rdf:resource="http://localhost:8080/"/>
<dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/7883/1/Do_H_ions_obscure.pdf"/>
<dc:language>eng</dc:language>
<void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
<dcterms:bibliographicCitation>First publ. in: FEBS Letters 532 (2002), pp. 198-202</dcterms:bibliographicCitation>
<dcterms:title>Do H+ ions obscure electrogenic Na+ and K+ binding in the E1 state of the Na,K-ATPase?</dcterms:title>
<dcterms:abstract xml:lang="eng">In contrast to other P-type ATPases, the Na,K-ATPase binding and release of ions on the cytoplasmic side, to the state called E1, is not electrogenic with the exception of the third Na+. Since the high-resolution structure of the closely related SR Ca-ATPase in state E1 revealed the ion-binding sites deep inside the transmembrane part of the protein, the missing electrogenicity in state E1 can be explained by an obscuring counter-movement of H+ ions. Evidence for such a mechanism is presented by analysis of pH effects of Na+ and K+ binding and by electrogenic H+ movements in the E1 conformation of the Na,K-ATPase.</dcterms:abstract>
<dc:contributor>Diller, Anna</dc:contributor>
<dc:contributor>Apell, Hans-Jürgen</dc:contributor>
<dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
<bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/7883"/>
</rdf:Description>
</rdf:RDF>Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
