Dance with spins : site-directed spin labeling coupled to electron paramagnetic resonance spectroscopy directly inside cells

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Chemical Communications. Royal Society of Chemistry (RSC). 2023, 59(10), pp. 1274-1284. ISSN 1359-7345. eISSN 1364-548X. Available under: doi: 10.1039/D2CC05907J
Zusammenfassung

Depicting how biomolecules move and interact within their physiological environment is one of the hottest topics of structural biology. This Feature Article gives an overview of the most recent advances in Site-directed Spin Labeling coupled to Electron Paramagnetic Resonance spectroscopy (SDSL–EPR) to study biomolecules in living cells. The high sensitivity, the virtual absence of background, and the versatility of spin-labeling strategies make this approach one of the most promising techniques for the study of biomolecules in physiologically relevant environments. After presenting the milestones achieved in this field, we present a summary of the future goals and ambitions of this community.

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ISO 690PIERRO, Annalisa, Malte DRESCHER, 2023. Dance with spins : site-directed spin labeling coupled to electron paramagnetic resonance spectroscopy directly inside cells. In: Chemical Communications. Royal Society of Chemistry (RSC). 2023, 59(10), pp. 1274-1284. ISSN 1359-7345. eISSN 1364-548X. Available under: doi: 10.1039/D2CC05907J
BibTex
@article{Pierro2023Dance-66211,
  year={2023},
  doi={10.1039/D2CC05907J},
  title={Dance with spins : site-directed spin labeling coupled to electron paramagnetic resonance spectroscopy directly inside cells},
  number={10},
  volume={59},
  issn={1359-7345},
  journal={Chemical Communications},
  pages={1274--1284},
  author={Pierro, Annalisa and Drescher, Malte}
}
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