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Directed motion of proteins along tethered polyelectrolytes

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Directed motion of proteins along tethered polyelectrolytes_PRL 2008.pdf
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Datum

2008

Autor:innen

Henzler, Katja
Rosenfeldt, Sabine
Harnau, Ludger
Finet, Stephanie
Narayanan, Theyencheri
Ballauff, Matthias

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http://nbn-resolving.de/urn:nbn:de:bsz:352-201927
DOI (zitierfähiger Link)
https://doi.org/10.1103/PhysRevLett.100.158301
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Chemie: Publikationen
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Published

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Physical Review Letters. 2008, 100(15). ISSN 0031-9007. Available under: doi: 10.1103/PhysRevLett.100.158301

Zusammenfassung

We present the first time-resolved investigation of motions of proteins in densely grafted layers of spherical polyelectrolyte brushes. Using small-angle x-ray scattering combined with rapid stopped-flow mixing, we followed the uptake of bovine serum albumin by poly(acrylic acid) layer with high spatial and temporal resolution. We find that the total amount of adsorbed protein scales with time as t1/4. This subdiffusive behavior is explained on the basis of directed motion of the protein along the polyelectrolyte chains.

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540 Chemie

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ISO 690HENZLER, Katja, Sabine ROSENFELDT, Alexander WITTEMANN, Ludger HARNAU, Stephanie FINET, Theyencheri NARAYANAN, Matthias BALLAUFF, 2008. Directed motion of proteins along tethered polyelectrolytes. In: Physical Review Letters. 2008, 100(15). ISSN 0031-9007. Available under: doi: 10.1103/PhysRevLett.100.158301
BibTex
@article{Henzler2008Direc-20192,
  year={2008},
  doi={10.1103/PhysRevLett.100.158301},
  title={Directed motion of proteins along tethered polyelectrolytes},
  number={15},
  volume={100},
  issn={0031-9007},
  journal={Physical Review Letters},
  author={Henzler, Katja and Rosenfeldt, Sabine and Wittemann, Alexander and Harnau, Ludger and Finet, Stephanie and Narayanan, Theyencheri and Ballauff, Matthias}
}
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