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Thermal Denaturation of DNA Studied with Neutron Scattering

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2011

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Wildes, Andrew
Valle-Orero, Jessica
Cuesta-López, Santiago
Garden, Jean-Luc
Peyrard, Michel

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https://doi.org/10.1103/PhysRevLett.106.048101
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http://arxiv.org/abs/1101.1797

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Physical Review Letters. American Physical Society (APS). 2011, 106(4), 048101. ISSN 0031-9007. eISSN 1079-7114. Available under: doi: 10.1103/PhysRevLett.106.048101

Zusammenfassung

The melting transition of DNA, whereby the strands of the double-helix structure completely separate at a certain temperature, has been characterized using neutron scattering. A Bragg peak from B-form fiber DNA has been measured as a function of temperature, and its widths and integrated intensities have been interpreted using the Peyrard-Bishop-Dauxois model with only one free parameter. The experiment is unique, as it gives spatial correlation along the molecule through the melting transition where other techniques cannot.

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ISO 690WILDES, Andrew, Nikos THEODORAKOPOULOS, Jessica VALLE-ORERO, Santiago CUESTA-LÓPEZ, Jean-Luc GARDEN, Michel PEYRARD, 2011. Thermal Denaturation of DNA Studied with Neutron Scattering. In: Physical Review Letters. American Physical Society (APS). 2011, 106(4), 048101. ISSN 0031-9007. eISSN 1079-7114. Available under: doi: 10.1103/PhysRevLett.106.048101
BibTex
@article{Wildes2011-01-28Therm-50324,
  year={2011},
  doi={10.1103/PhysRevLett.106.048101},
  title={Thermal Denaturation of DNA Studied with Neutron Scattering},
  number={4},
  volume={106},
  issn={0031-9007},
  journal={Physical Review Letters},
  author={Wildes, Andrew and Theodorakopoulos, Nikos and Valle-Orero, Jessica and Cuesta-López, Santiago and Garden, Jean-Luc and Peyrard, Michel},
  note={Article Number: 048101}
}
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