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Diffusing-wave spectroscopy from head-like tissue phantoms : influence of a non-scattering layer

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Diffusing_wave_spectroscopy_from_head_like_tissue_phantoms.pdf
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2006

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Jaillon, Franck
Skipetrov, Sergey E.
Dietsche, Gregor

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http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-54186
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https://doi.org/10.1364/OE.14.010181
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Attribution-NonCommercial-NoDerivs 2.0 Generic

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Optics Express. 2006, 14(22), pp. 10181-10194. Available under: doi: 10.1364/OE.14.010181

Zusammenfassung

We investigate the influence of a non-scattering layer on the temporal field autocorrelation function of multiple scattered light g (1)(r,τ ) from a multilayer turbid medium such as the human head. Data from Monte Carlo simulations show very good agreement with the predictions of the correlation-diffusion equation with boundary conditions taking into account non-diffusive light transport within the non-scattering layer. Field autocorrelation functions measured at the surface of a multilayer phantom including a non-scattering layer agree well with theory and simulations when the source-receiver distance is significantly larger than the depth and the thickness of the non-scattering layer. Our results show that for sourcereceiver distances large enough to probe the dynamics in the human cortex, the cortical diffusion coefficient obtained by analyzing field autocorrelation functions neglecting the presence of the non-scattering cerebrospinal fluid layer is underestimated by about 40% in situations representative of the human head.

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530 Physik

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ISO 690JAILLON, Franck, Sergey E. SKIPETROV, Jun LI, Gregor DIETSCHE, Georg MARET, Thomas GISLER, 2006. Diffusing-wave spectroscopy from head-like tissue phantoms : influence of a non-scattering layer. In: Optics Express. 2006, 14(22), pp. 10181-10194. Available under: doi: 10.1364/OE.14.010181
BibTex
@article{Jaillon2006Diffu-9092,
  year={2006},
  doi={10.1364/OE.14.010181},
  title={Diffusing-wave spectroscopy from head-like tissue phantoms : influence of a non-scattering layer},
  number={22},
  volume={14},
  journal={Optics Express},
  pages={10181--10194},
  author={Jaillon, Franck and Skipetrov, Sergey E. and Li, Jun and Dietsche, Gregor and Maret, Georg and Gisler, Thomas}
}
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