Publikation: Childhood stress and psychiatric disorder modifiy reward processing
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Altered functioning of the reward system is assumed for individuals with mental disorders relative to normals, but also as a consequence of stressful experiences. Using a gambling design to produce reward processing, the present magnetoencephalographic (MEG) study examined brain activity during value appraisal and reward expectation in 22 patients with psychiatric diagnoses (MDD, schizophrenia, BPD, addiction) and 12 healthy subjects. The life-stress interview determined high childhood stress in 11 and low stress in 11 patients and the healthy subjects. DuringMEG-recording, subjects decided, whether or not to gamble for 10 or 50 c, which they could win with 10%, 50% or 90% chance, with value and chance being represented by visual cues. All subjects showed more posterior temporal activity to cues for higher value.
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STEFFEN, Astrid, Katharina MATZ, Christine NAEGELE, Brigitte ROCKSTROH, 2009. Childhood stress and psychiatric disorder modifiy reward processing. In: Psychophysiology. 2009, 46(Suppl. 1), pp. S90BibTex
@article{Steffen2009Child-1381, year={2009}, title={Childhood stress and psychiatric disorder modifiy reward processing}, number={Suppl. 1}, volume={46}, journal={Psychophysiology}, author={Steffen, Astrid and Matz, Katharina and Naegele, Christine and Rockstroh, Brigitte} }
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