Publikation: Alu insertion polymorphisms shared by Papio baboons and Theropithecus gelada reveal an intertwined common ancestry
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Baboons (genus Papio) and geladas (Theropithecus gelada) are now generally recognized as close phylogenetic relatives, though morphologically quite distinct and generally classified in separate genera. Primate specific Alu retrotransposons are well-established genomic markers for the study of phylogenetic and population genetic relationships. We previously reported a computational reconstruction of Papio phylogeny using large-scale whole genome sequence (WGS) analysis of Alu insertion polymorphisms. Recently, high coverage WGS was generated for Theropithecus gelada. The objective of this study was to apply the high-throughput "poly-Detect" method to computationally determine the number of Alu insertion polymorphisms shared by T. gelada and Papio, and vice versa, by each individual Papio species and T. gelada. Secondly, we performed locus-specific polymerase chain reaction (PCR) assays on a diverse DNA panel to complement the computational data.
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WALKER, Jerilyn A., Vallmer E. JORDAN, Jessica M. STORER, Cody J. STEELY, Paulina GONZALEZ-QUIROGA, Thomas O. BECKSTROM, Mark A. BATZER, Gisela H. KOPP, Angela NOLL, Christian ROOS, 2019. Alu insertion polymorphisms shared by Papio baboons and Theropithecus gelada reveal an intertwined common ancestry. In: Mobile DNA. 2019, 10(1), 46 (2019). ISSN 1759-8753. eISSN 1759-8753. Available under: doi: 10.1186/s13100-019-0187-yBibTex
@article{Walker2019inser-48750, year={2019}, doi={10.1186/s13100-019-0187-y}, title={Alu insertion polymorphisms shared by Papio baboons and Theropithecus gelada reveal an intertwined common ancestry}, number={1}, volume={10}, issn={1759-8753}, journal={Mobile DNA}, author={Walker, Jerilyn A. and Jordan, Vallmer E. and Storer, Jessica M. and Steely, Cody J. and Gonzalez-Quiroga, Paulina and Beckstrom, Thomas O. and Batzer, Mark A. and Kopp, Gisela H. and Noll, Angela and Roos, Christian}, note={Article Number: 46 (2019)} }
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