@article{Hanslmayr2012-10-17Prefr-20739,
  year={2012},
  doi={10.1523/JNEUROSCI.1777-12.2012},
  title={Prefrontally Driven Downregulation of Neural Synchrony Mediates Goal-Directed Forgetting},
  number={42},
  volume={32},
  issn={0270-6474},
  journal={Journal of Neuroscience},
  pages={14742--14751},
  author={Hanslmayr, Simon and Volberg, Gregor and Wimber, Maria and Oehler, Nora and Staudigl, Tobias and Hartmann, Thomas and Raabe, Markus and Greenlee, Mark and Bäuml, Karl-Heinz}
}

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    <dc:contributor>Staudigl, Tobias</dc:contributor>
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    <dcterms:abstract xml:lang="eng">Neural synchronization between distant cell assemblies is crucial for the formation of new memories. To date, however, it remains unclear whether higher-order brain regions can adaptively regulate neural synchrony to control memory processing in humans. We explored this question in two experiments using a voluntary forgetting task. In the first experiment, we simultaneously recorded electroencephalography along with fMRI. The results show that a reduction in neural synchrony goes hand-in-hand with a BOLD signal increase in the left dorsolateral prefrontal cortex (dlPFC) when participants are cued to forget previously studied information. In the&lt;br /&gt;second experiment, we directly stimulated the left dlPFC with repetitive transcranial magnetic stimulation during the same task, and show that such stimulation specifically boosts the behavioral forgetting effect and induces a reduction in neural synchrony. These results suggest that prefrontally driven downregulation of long-range neural synchronization mediates goal-directed forgetting of long-term memories.</dcterms:abstract>
    <dc:creator>Bäuml, Karl-Heinz</dc:creator>
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    <dc:contributor>Volberg, Gregor</dc:contributor>
    <dc:contributor>Oehler, Nora</dc:contributor>
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    <dcterms:bibliographicCitation>The Journal of Neuroscience ; 32 (2012), 42. - S. 14742-14751</dcterms:bibliographicCitation>
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