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Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M

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2011

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Rusch, Marion
Zimmermann, Tobias J.
Bürger, Marco
Dekker, Frank J.
Görmer, Kristina
Triola, Gemma
Brockmeyer, Andreas
Janning, Petra
Sieber, Stephan A.
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http://nbn-resolving.de/urn:nbn:de:bsz:352-284386
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https://doi.org/10.1002/anie.201102967
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Chemie: Publikationen
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Angewandte Chemie International Edition. 2011, 50(42), pp. 9838-9842. ISSN 1433-7851. eISSN 1521-3773. Available under: doi: 10.1002/anie.201102967

Zusammenfassung

Finding the target: activity-based proteomic profiling probes based on the depalmitoylation inhibitors palmostatin B and M have been synthesized and were found to target acyl protein thioesterase 1 (APT1) and 2 (APT2) in cells.

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540 Chemie

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ISO 690RUSCH, Marion, Tobias J. ZIMMERMANN, Marco BÜRGER, Frank J. DEKKER, Kristina GÖRMER, Gemma TRIOLA, Andreas BROCKMEYER, Petra JANNING, Thomas BÖTTCHER, Stephan A. SIEBER, Ingrid R. VETTER, Christian HEDBERG, Herbert WALDMANN, 2011. Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M. In: Angewandte Chemie International Edition. 2011, 50(42), pp. 9838-9842. ISSN 1433-7851. eISSN 1521-3773. Available under: doi: 10.1002/anie.201102967
BibTex
@article{Rusch2011-10-10Ident-28438,
  year={2011},
  doi={10.1002/anie.201102967},
  title={Identification of Acyl Protein Thioesterases 1 and 2 as the Cellular Targets of the Ras-Signaling Modulators Palmostatin B and M},
  number={42},
  volume={50},
  issn={1433-7851},
  journal={Angewandte Chemie International Edition},
  pages={9838--9842},
  author={Rusch, Marion and Zimmermann, Tobias J. and Bürger, Marco and Dekker, Frank J. and Görmer, Kristina and Triola, Gemma and Brockmeyer, Andreas and Janning, Petra and Böttcher, Thomas and Sieber, Stephan A. and Vetter, Ingrid R. and Hedberg, Christian and Waldmann, Herbert}
}
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