Publikation: Features of the behavior of 4-amino-5-carboxamido-1,2,3-triazole in multicomponent heterocyclizations with carbonyl compounds
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2012
Autor:innen
Gladkov, Eugene S.
Gura, Katerina A.
Sirko, Svetlana M.
Desenko, Sergey M.
Chebanov, Valentin A.
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Published
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Beilstein Journal of Organic Chemistry. 2012, 8, pp. 2100-2105. eISSN 1860-5397. Available under: doi: 10.3762/bjoc.8.236
Zusammenfassung
Multicomponent reactions involving polyfunctional 4-amino-5-carboxamido-1,2,3-triazole and cyclic carbonyl-containing CH-acids were studied under conventional thermal heating, microwave and ultrasonic irradiation. The features of the reactions studied were discussed and the optimized procedures for the synthesis of final triazolopyrimidines were elaborated. In contrast to the similar MCRs of numerous other aminoazoles, a change of direction of the heterocyclizations in the case of 4-amino-5-carboxamido-1,2,3-triazole was not observed when microwave or thermal heating was substituted by ultrasonication at ambient temperature.
Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
540 Chemie
Schlagwörter
4-amino-5-carboxamido-1, 2, 3-triazole, heterocycle, microwave-assisted synthesis, multicomponent reaction, ultrasound-assisted synthesis
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GLADKOV, Eugene S., Katerina A. GURA, Svetlana M. SIRKO, Sergey M. DESENKO, Ulrich GROTH, Valentin A. CHEBANOV, 2012. Features of the behavior of 4-amino-5-carboxamido-1,2,3-triazole in multicomponent heterocyclizations with carbonyl compounds. In: Beilstein Journal of Organic Chemistry. 2012, 8, pp. 2100-2105. eISSN 1860-5397. Available under: doi: 10.3762/bjoc.8.236BibTex
@article{Gladkov2012Featu-22617,
year={2012},
doi={10.3762/bjoc.8.236},
title={Features of the behavior of 4-amino-5-carboxamido-1,2,3-triazole in multicomponent heterocyclizations with carbonyl compounds},
volume={8},
journal={Beilstein Journal of Organic Chemistry},
pages={2100--2105},
author={Gladkov, Eugene S. and Gura, Katerina A. and Sirko, Svetlana M. and Desenko, Sergey M. and Groth, Ulrich and Chebanov, Valentin A.}
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