Growth produces coordination trade-offs in Trichoplax adhaerens, an animal lacking a central nervous system

Lade...
Vorschaubild
Dateien
Davidescu_2-jrwy59vei06u0.pdf
Davidescu_2-jrwy59vei06u0.pdfGröße: 2.48 MBDownloads: 18
Datum
2023
Autor:innen
Davidescu, Mircea R.
Romanczuk, Pawel
Gregor, Thomas
Herausgeber:innen
Kontakt
ISSN der Zeitschrift
Electronic ISSN
ISBN
Bibliografische Daten
Verlag
Schriftenreihe
Auflagebezeichnung
ArXiv-ID
Internationale Patentnummer
Link zur Lizenz
Angaben zur Forschungsförderung
European Union (EU): 860949
Projekt
Open Access-Veröffentlichung
Open Access Hybrid
Core Facility der Universität Konstanz
Gesperrt bis
Titel in einer weiteren Sprache
Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published
Erschienen in
Proceedings of the National Academy of Sciences of the United States of America (PNAS). National Academy of Sciences. 2023, 120(11), e2206163120. ISSN 0027-8424. eISSN 1091-6490. Available under: doi: 10.1073/pnas.2206163120
Zusammenfassung

How collectives remain coordinated as they grow in size is a fundamental challenge affecting systems ranging from biofilms to governments. This challenge is particularly apparent in multicellular organisms, where coordination among a vast number of cells is vital for coherent animal behavior. However, the earliest multicellular organisms were decentralized, with indeterminate sizes and morphologies, as exemplified by Trichoplax adhaerens , arguably the earliest-diverged and simplest motile animal. We investigated coordination among cells in T. adhaerens by observing the degree of collective order in locomotion across animals of differing sizes and found that larger individuals exhibit increasingly disordered locomotion. We reproduced this effect of size on order through a simulation model of active elastic cellular sheets and demonstrate that this relationship is best recapitulated across all body sizes when the simulation parameters are tuned to a critical point in the parameter space. We quantify the trade-off between increasing size and coordination in a multicellular animal with a decentralized anatomy that shows evidence of criticality and hypothesize as to the implications of this on the evolution hierarchical structures such as nervous systems in larger organisms.

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
570 Biowissenschaften, Biologie
Schlagwörter
Konferenz
Rezension
undefined / . - undefined, undefined
Forschungsvorhaben
Organisationseinheiten
Zeitschriftenheft
Datensätze
Zitieren
ISO 690DAVIDESCU, Mircea R., Pawel ROMANCZUK, Thomas GREGOR, Iain D. COUZIN, 2023. Growth produces coordination trade-offs in Trichoplax adhaerens, an animal lacking a central nervous system. In: Proceedings of the National Academy of Sciences of the United States of America (PNAS). National Academy of Sciences. 2023, 120(11), e2206163120. ISSN 0027-8424. eISSN 1091-6490. Available under: doi: 10.1073/pnas.2206163120
BibTex
@article{Davidescu2023-03-10Growt-66445,
  year={2023},
  doi={10.1073/pnas.2206163120},
  title={Growth produces coordination trade-offs in Trichoplax adhaerens, an animal lacking a central nervous system},
  number={11},
  volume={120},
  issn={0027-8424},
  journal={Proceedings of the National Academy of Sciences of the United States of America (PNAS)},
  author={Davidescu, Mircea R. and Romanczuk, Pawel and Gregor, Thomas and Couzin, Iain D.},
  note={Article Number: e2206163120}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/66445">
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2023-03-20T16:13:11Z</dcterms:available>
    <dc:creator>Romanczuk, Pawel</dc:creator>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2023-03-20T16:13:11Z</dc:date>
    <dc:rights>Attribution 4.0 International</dc:rights>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/66445/1/Davidescu_2-jrwy59vei06u0.pdf"/>
    <dc:contributor>Gregor, Thomas</dc:contributor>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/66445/1/Davidescu_2-jrwy59vei06u0.pdf"/>
    <dc:contributor>Couzin, Iain D.</dc:contributor>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/66445"/>
    <dc:contributor>Davidescu, Mircea R.</dc:contributor>
    <dcterms:title>Growth produces coordination trade-offs in Trichoplax adhaerens, an animal lacking a central nervous system</dcterms:title>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:language>eng</dc:language>
    <dc:creator>Davidescu, Mircea R.</dc:creator>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43615"/>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/28"/>
    <dc:creator>Gregor, Thomas</dc:creator>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43615"/>
    <dcterms:abstract>How collectives remain coordinated as they grow in size is a fundamental challenge affecting systems ranging from biofilms to governments. This challenge is particularly apparent in multicellular organisms, where coordination among a vast number of cells is vital for coherent animal behavior. However, the earliest multicellular organisms were decentralized, with indeterminate sizes and morphologies, as exemplified by Trichoplax adhaerens       , arguably the earliest-diverged and simplest motile animal. We investigated coordination among cells in T. adhaerens by observing the degree of collective order in locomotion across animals of differing sizes and found that larger individuals exhibit increasingly disordered locomotion. We reproduced this effect of size on order through a simulation model of active elastic cellular sheets and demonstrate that this relationship is best recapitulated across all body sizes when the simulation parameters are tuned to a critical point in the parameter space. We quantify the trade-off between increasing size and coordination in a multicellular animal with a decentralized anatomy that shows evidence of criticality and hypothesize as to the implications of this on the evolution hierarchical structures such as nervous systems in larger organisms.</dcterms:abstract>
    <dc:creator>Couzin, Iain D.</dc:creator>
    <dc:contributor>Romanczuk, Pawel</dc:contributor>
    <dcterms:rights rdf:resource="http://creativecommons.org/licenses/by/4.0/"/>
    <dcterms:issued>2023-03-10</dcterms:issued>
  </rdf:Description>
</rdf:RDF>
Interner Vermerk
xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter
Kontakt
URL der Originalveröffentl.
Prüfdatum der URL
Prüfungsdatum der Dissertation
Finanzierungsart
Kommentar zur Publikation
Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Ja
Link zu Forschungsdaten
Beschreibung der Forschungsdaten
Data used for the production of this paper are available on Zenodo
Diese Publikation teilen