Features of two- and multicomponent heterocyclization reactions involving 3,4-disubstituted 5-aminopyrazoles and alkyl pyruvates

Kurzanzeige
dc.contributor.authorSakhno, Yana I.
dc.contributor.authorKozyryev, Anton V.
dc.contributor.authorDesenko, Sergey M.
dc.contributor.authorShishkina, Svetlana V.
dc.contributor.authorMusatov, Vladimir I.
dc.contributor.authorSysoiev, Dmytro
dc.contributor.authorChebanov, Valentin A.
dc.date.accessioned2018-02-16T09:24:37Z
dc.date.available2018-02-16T09:24:37Z
dc.date.issued2018-02eng
dc.description.abstractThree-component heterocyclizations of pyruvic acids and their esters with 5-aminopyrazoles and aromatic aldehydes, in addition to the sequential versions of these reactions, under different activating conditions were studied. Under conventional heating, pyrazolopyrimidine derivatives containing a hydroxyl group in the 6-position were formed in both two- and three-component treatments. Whereas the application of an inert atmosphere did not influence the outcome of these reactions, the use of ultrasonic irradiation led to the formation of 7-hydroxy-tetrahydropyrazolopyrimidines in multi-component reactions and 6-hydroxy-dihydropyrazolopyrimidines in the case of a step-by-step approach. The products of the latter treatment were further transformed into heteroaromatized 6-hydroxy-pyrazolopyrimidines by conventional heating.eng
dc.description.versionpublishedde
dc.identifier.doi10.1016/j.tet.2017.12.031eng
dc.identifier.urihttps://kops.uni-konstanz.de/handle/123456789/41405
dc.language.isoengeng
dc.subject.ddc540eng
dc.titleFeatures of two- and multicomponent heterocyclization reactions involving 3,4-disubstituted 5-aminopyrazoles and alkyl pyruvateseng
dc.typeJOURNAL_ARTICLEde
dspace.entity.typePublication
kops.citation.bibtex
@article{Sakhno2018-02Featu-41405,
  year={2018},
  doi={10.1016/j.tet.2017.12.031},
  title={Features of two- and multicomponent heterocyclization reactions involving 3,4-disubstituted 5-aminopyrazoles and alkyl pyruvates},
  number={5},
  volume={74},
  issn={0040-4020},
  journal={Tetrahedron},
  pages={564--571},
  author={Sakhno, Yana I. and Kozyryev, Anton V. and Desenko, Sergey M. and Shishkina, Svetlana V. and Musatov, Vladimir I. and Sysoiev, Dmytro and Chebanov, Valentin A.}
}
kops.citation.iso690SAKHNO, Yana I., Anton V. KOZYRYEV, Sergey M. DESENKO, Svetlana V. SHISHKINA, Vladimir I. MUSATOV, Dmytro SYSOIEV, Valentin A. CHEBANOV, 2018. Features of two- and multicomponent heterocyclization reactions involving 3,4-disubstituted 5-aminopyrazoles and alkyl pyruvates. In: Tetrahedron. 2018, 74(5), pp. 564-571. ISSN 0040-4020. eISSN 1464-5416. Available under: doi: 10.1016/j.tet.2017.12.031deu
kops.citation.iso690SAKHNO, Yana I., Anton V. KOZYRYEV, Sergey M. DESENKO, Svetlana V. SHISHKINA, Vladimir I. MUSATOV, Dmytro SYSOIEV, Valentin A. CHEBANOV, 2018. Features of two- and multicomponent heterocyclization reactions involving 3,4-disubstituted 5-aminopyrazoles and alkyl pyruvates. In: Tetrahedron. 2018, 74(5), pp. 564-571. ISSN 0040-4020. eISSN 1464-5416. Available under: doi: 10.1016/j.tet.2017.12.031eng
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