Publikation:

Assimilation of homotaurine-nitrogen by Burkholderia sp. and excretion of sulfopropanoate

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2008

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Kaspar, Katrin
Hollemeyer, Klaus
Smits, Theo H. M.

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FEMS Microbiology Letters. 2008, 279(1), pp. 77-82. ISSN 0378-1097. eISSN 1574-6968. Available under: doi: 10.1111/j.1574-6968.2007.01014.x

Zusammenfassung

Homotaurine (3-aminopropanesulfonate), free or derivatized, is in widespread pharmaceutical and laboratory use. Studies with enrichment cultures indicated that the compound is degradable as a sole source of carbon or as a sole source of nitrogen for bacterial growth. A pure culture of Burkholderia sp. was isolated which assimilated the amino group from homotaurine in a glucose-salts medium, and which released an organosulfonate, 3-sulfopropanoate, into the medium stoichiometrically. The deamination involved an inducible 2-oxoglutarate-dependent aminotransferase to yield glutamate, and 3-sulfopropanal. Release of the amino group was attributed to the measured NADP-coupled glutamate dehydrogenase.

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Fachgebiet (DDC)
570 Biowissenschaften, Biologie

Schlagwörter

assimilation of homotaurine-nitrogen, Burkholderia sp., excretion of sulfopropanoate, homotaurine:2-oxoglutarate aminotransferase

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ISO 690MAYER, Jutta, Karin DENGER, Katrin KASPAR, Klaus HOLLEMEYER, Theo H. M. SMITS, Thomas HUHN, Alasdair M. COOK, 2008. Assimilation of homotaurine-nitrogen by Burkholderia sp. and excretion of sulfopropanoate. In: FEMS Microbiology Letters. 2008, 279(1), pp. 77-82. ISSN 0378-1097. eISSN 1574-6968. Available under: doi: 10.1111/j.1574-6968.2007.01014.x
BibTex
@article{Mayer2008Assim-9625,
  year={2008},
  doi={10.1111/j.1574-6968.2007.01014.x},
  title={Assimilation of homotaurine-nitrogen by Burkholderia sp. and excretion of sulfopropanoate},
  number={1},
  volume={279},
  issn={0378-1097},
  journal={FEMS Microbiology Letters},
  pages={77--82},
  author={Mayer, Jutta and Denger, Karin and Kaspar, Katrin and Hollemeyer, Klaus and Smits, Theo H. M. and Huhn, Thomas and Cook, Alasdair M.}
}
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