Publikation: Assimilation of homotaurine-nitrogen by Burkholderia sp. and excretion of sulfopropanoate
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Homotaurine (3-aminopropanesulfonate), free or derivatized, is in widespread pharmaceutical and laboratory use. Studies with enrichment cultures indicated that the compound is degradable as a sole source of carbon or as a sole source of nitrogen for bacterial growth. A pure culture of Burkholderia sp. was isolated which assimilated the amino group from homotaurine in a glucose-salts medium, and which released an organosulfonate, 3-sulfopropanoate, into the medium stoichiometrically. The deamination involved an inducible 2-oxoglutarate-dependent aminotransferase to yield glutamate, and 3-sulfopropanal. Release of the amino group was attributed to the measured NADP-coupled glutamate dehydrogenase.
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MAYER, Jutta, Karin DENGER, Katrin KASPAR, Klaus HOLLEMEYER, Theo H. M. SMITS, Thomas HUHN, Alasdair M. COOK, 2008. Assimilation of homotaurine-nitrogen by Burkholderia sp. and excretion of sulfopropanoate. In: FEMS Microbiology Letters. 2008, 279(1), pp. 77-82. ISSN 0378-1097. eISSN 1574-6968. Available under: doi: 10.1111/j.1574-6968.2007.01014.xBibTex
@article{Mayer2008Assim-9625, year={2008}, doi={10.1111/j.1574-6968.2007.01014.x}, title={Assimilation of homotaurine-nitrogen by Burkholderia sp. and excretion of sulfopropanoate}, number={1}, volume={279}, issn={0378-1097}, journal={FEMS Microbiology Letters}, pages={77--82}, author={Mayer, Jutta and Denger, Karin and Kaspar, Katrin and Hollemeyer, Klaus and Smits, Theo H. M. and Huhn, Thomas and Cook, Alasdair M.} }
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