Facile Synthesis of Fluorinated 1-Desazapurines

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Date
2009
Authors
Iaroshenko, Viktor O.
Sevenard, Dmitri V.
Volochnyuk, Dmitriy M.
Martiloga, Alexander
Tolmachev, Andrei O.
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Synthesis ; 2009 (2009), 11. - pp. 1865-1875. - Georg Thieme Verlag. - ISSN 0039-7881. - eISSN 1437-210X
Abstract
A preparative approach towards 1-desazapurines, starting from 4(5)-aminoimidazoles and polyfluoroalkyl-containing 1,3-CCC-biselectrophiles was developed. As a result, a set of fluorinated 1-desazapurines was synthesized. Additionally, a synthetic route to 1-desazapurines bearing a sugar-mimicking group is proposed.
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540 Chemistry
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ISO 690IAROSHENKO, Viktor O., Dmitri V. SEVENARD, Dmitriy M. VOLOCHNYUK, Yan WANG, Alexander MARTILOGA, Andrei O. TOLMACHEV, 2009. Facile Synthesis of Fluorinated 1-Desazapurines. In: Synthesis. Georg Thieme Verlag. 2009(11), pp. 1865-1875. ISSN 0039-7881. eISSN 1437-210X. Available under: doi: 10.1055/s-0029-1216802
BibTex
@article{Iaroshenko2009Facil-58517,
  year={2009},
  doi={10.1055/s-0029-1216802},
  title={Facile Synthesis of Fluorinated 1-Desazapurines},
  number={11},
  volume={2009},
  issn={0039-7881},
  journal={Synthesis},
  pages={1865--1875},
  author={Iaroshenko, Viktor O. and Sevenard, Dmitri V. and Volochnyuk, Dmitriy M. and Wang, Yan and Martiloga, Alexander and Tolmachev, Andrei O.}
}
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