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Site-directed spin labeling of proteins for distance measurements in vitro and in cells

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Roser_0-348649.pdf
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2016

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Organic & Biomolecular Chemistry. 2016, 14(24), pp. 5468-5476. ISSN 1477-0520. eISSN 1477-0539. Available under: doi: 10.1039/c6ob00473c

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Site-directed spin labeling (SDSL) in combination with electron paramagnetic resonance (EPR) spectroscopy allows studying the structure, dynamics, and interactions of proteins via distance measurements in the nanometer range. We here give an overview of available spin labels, the strategies for their introduction into proteins, and the associated potentials for protein structural studies in vitro and in the context of living cells.

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540 Chemie

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ISO 690ROSER, Patrick, Moritz J. SCHMIDT, Malte DRESCHER, Daniel SUMMERER, 2016. Site-directed spin labeling of proteins for distance measurements in vitro and in cells. In: Organic & Biomolecular Chemistry. 2016, 14(24), pp. 5468-5476. ISSN 1477-0520. eISSN 1477-0539. Available under: doi: 10.1039/c6ob00473c
BibTex
@article{Roser2016Sited-35384,
  year={2016},
  doi={10.1039/c6ob00473c},
  title={Site-directed spin labeling of proteins for distance measurements in vitro and in cells},
  number={24},
  volume={14},
  issn={1477-0520},
  journal={Organic & Biomolecular Chemistry},
  pages={5468--5476},
  author={Roser, Patrick and Schmidt, Moritz J. and Drescher, Malte and Summerer, Daniel}
}
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