Publikation:

Nucleus accumbens activation is linked to salience in social decision making

Vorschaubild

Dateien

Schmidt_2-d5td16ucrx5z0.pdf
Schmidt_2-d5td16ucrx5z0.pdfGröße: 646.4 KBDownloads: 606

Datum

2019

Autor:innen

Fenske, Sabrina C.
Kirsch, Peter

Herausgeber:innen

Kontakt

ISSN der Zeitschrift

Electronic ISSN

ISBN

Bibliografische Daten

Verlag

Schriftenreihe

Auflagebezeichnung

URI (zitierfähiger Link)
http://nbn-resolving.de/urn:nbn:de:bsz:352-2-d5td16ucrx5z0
DOI (zitierfähiger Link)
https://doi.org/10.1007/s00406-018-0947-6
ArXiv-ID

Internationale Patentnummer

Link zur Lizenz
Urheberrechtlich geschützt

Angaben zur Forschungsförderung

Projekt

Open Access-Veröffentlichung
Open Access Green

Sammlungen

Psychologie: Publikationen
Core Facility der Universität Konstanz

Gesperrt bis

Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

European archives of psychiatry and clinical neuroscience. 2019, 269(6), pp. 701-712. ISSN 0940-1334. eISSN 1433-8491. Available under: doi: 10.1007/s00406-018-0947-6

Zusammenfassung

Aberrant salience may explain hasty decision making and psychotic symptoms in schizophrenia. In healthy individuals, final decisions in probabilistic reasoning tasks are related to Nucleus accumbens (Nacc) activation. However, research investigating the Nacc in social decision making is missing. Our study aimed at investigating the role of the Nacc for social decision making and its link to (aberrant) salience attribution. 47 healthy individuals completed a novel social jumping-to-conclusion (JTC) fMRI-paradigm, showing morphed faces simultaneously expressing fear and happiness. Participants decided on the 'current' emotion after each picture, and on the 'general' emotion of series of faces. Nacc activation was stronger during final decisions than in previous trials without a decision, particularly in fear rather than happiness series. A JTC-bias was associated with higher Nacc activation for last fearful, but not last happy faces. Apparently, mechanisms underlying probabilistic reasoning are also relevant for social decision making. The pattern of Nacc activation suggests salience, not reward, drives the final decision. Based on these findings, we hypothesize that aberrant salience might also explain social-cognitive deficits in schizophrenia.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
150 Psychologie

Schlagwörter

Emotion recognition, Decision making, Jumping-to-conclusion bias, Aberrant salience, Schizophrenia, Nucleus accumbens

Konferenz

Rezension
undefined / . - undefined, undefined

Forschungsvorhaben

Organisationseinheiten

Zeitschriftenheft

Zugehörige Datensätze in KOPS

Zitieren

ISO 690SCHMIDT, Stephanie N. L., Sabrina C. FENSKE, Peter KIRSCH, Daniela MIER, 2019. Nucleus accumbens activation is linked to salience in social decision making. In: European archives of psychiatry and clinical neuroscience. 2019, 269(6), pp. 701-712. ISSN 0940-1334. eISSN 1433-8491. Available under: doi: 10.1007/s00406-018-0947-6
BibTex
@article{Schmidt2019-09Nucle-45215,
  year={2019},
  doi={10.1007/s00406-018-0947-6},
  title={Nucleus accumbens activation is linked to salience in social decision making},
  number={6},
  volume={269},
  issn={0940-1334},
  journal={European archives of psychiatry and clinical neuroscience},
  pages={701--712},
  author={Schmidt, Stephanie N. L. and Fenske, Sabrina C. and Kirsch, Peter and Mier, Daniela}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/45215">
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
    <dc:creator>Mier, Daniela</dc:creator>
    <dc:contributor>Mier, Daniela</dc:contributor>
    <dc:rights>terms-of-use</dc:rights>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <bibo:uri rdf:resource="https://kops.uni-konstanz.de/handle/123456789/45215"/>
    <dcterms:hasPart rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/45215/1/Schmidt_2-d5td16ucrx5z0.pdf"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2019-02-26T08:53:18Z</dc:date>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2019-02-26T08:53:18Z</dcterms:available>
    <dcterms:title>Nucleus accumbens activation is linked to salience in social decision making</dcterms:title>
    <dc:creator>Fenske, Sabrina C.</dc:creator>
    <dc:creator>Kirsch, Peter</dc:creator>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/43"/>
    <dspace:hasBitstream rdf:resource="https://kops.uni-konstanz.de/bitstream/123456789/45215/1/Schmidt_2-d5td16ucrx5z0.pdf"/>
    <dc:contributor>Fenske, Sabrina C.</dc:contributor>
    <dc:contributor>Schmidt, Stephanie N. L.</dc:contributor>
    <dc:creator>Schmidt, Stephanie N. L.</dc:creator>
    <dcterms:abstract xml:lang="eng">Aberrant salience may explain hasty decision making and psychotic symptoms in schizophrenia. In healthy individuals, final decisions in probabilistic reasoning tasks are related to Nucleus accumbens (Nacc) activation. However, research investigating the Nacc in social decision making is missing. Our study aimed at investigating the role of the Nacc for social decision making and its link to (aberrant) salience attribution. 47 healthy individuals completed a novel social jumping-to-conclusion (JTC) fMRI-paradigm, showing morphed faces simultaneously expressing fear and happiness. Participants decided on the 'current' emotion after each picture, and on the 'general' emotion of series of faces. Nacc activation was stronger during final decisions than in previous trials without a decision, particularly in fear rather than happiness series. A JTC-bias was associated with higher Nacc activation for last fearful, but not last happy faces. Apparently, mechanisms underlying probabilistic reasoning are also relevant for social decision making. The pattern of Nacc activation suggests salience, not reward, drives the final decision. Based on these findings, we hypothesize that aberrant salience might also explain social-cognitive deficits in schizophrenia.</dcterms:abstract>
    <dc:language>eng</dc:language>
    <dcterms:issued>2019-09</dcterms:issued>
    <dc:contributor>Kirsch, Peter</dc:contributor>
  </rdf:Description>
</rdf:RDF>

Interner Vermerk

xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter

Kontakt
URL der Originalveröffentl.

Prüfdatum der URL

Prüfungsdatum der Dissertation

Finanzierungsart

Kommentar zur Publikation

Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Ja
Begutachtet
Ja
Diese Publikation teilen