VANTED v2 : a framework for systems biology applications

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Rohn_0-396017.pdf
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2012
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Rohn, Hendrik
Junker, Astrid
Hartmann, Anja
Grafahrend-Belau, Eva
Treutler, Hendrik
Klapperstück, Matthias
Czauderna, Tobias
Klukas, Christian
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Zusammenfassung

Background

Experimental datasets are becoming larger and increasingly complex, spanning different data domains, thereby expanding the requirements for respective tool support for their analysis. Networks provide a basis for the integration, analysis and visualization of multi-omics experimental datasets.

Results

Here we present Vanted (version 2), a framework for systems biology applications, which comprises a comprehensive set of seven main tasks. These range from network reconstruction, data visualization, integration of various data types, network simulation to data exploration combined with a manifold support of systems biology standards for visualization and data exchange. The offered set of functionalities is instantiated by combining several tasks in order to enable users to view and explore a comprehensive dataset from different perspectives. We describe the system as well as an exemplary workflow.

Conclusions

Vanted is a stand-alone framework which supports scientists during the data analysis and interpretation phase. It is available as a Java open source tool from http://www.vanted.org

Zusammenfassung in einer weiteren Sprache
Fachgebiet (DDC)
004 Informatik
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Biological networks, Data visualization, Data integratio,n Data analysis, Omics, Model simulation
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ISO 690ROHN, Hendrik, Astrid JUNKER, Anja HARTMANN, Eva GRAFAHREND-BELAU, Hendrik TREUTLER, Matthias KLAPPERSTÜCK, Tobias CZAUDERNA, Christian KLUKAS, Falk SCHREIBER, 2012. VANTED v2 : a framework for systems biology applications. In: BMC Systems Biology. 2012, 6(1), 139. eISSN 1752-0509. Available under: doi: 10.1186/1752-0509-6-139
BibTex
@article{Rohn2012VANTE-38598,
  year={2012},
  doi={10.1186/1752-0509-6-139},
  title={VANTED v2 : a framework for systems biology applications},
  number={1},
  volume={6},
  journal={BMC Systems Biology},
  author={Rohn, Hendrik and Junker, Astrid and Hartmann, Anja and Grafahrend-Belau, Eva and Treutler, Hendrik and Klapperstück, Matthias and Czauderna, Tobias and Klukas, Christian and Schreiber, Falk},
  note={Article Number: 139}
}
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