Publikation:

Reporter ribozymes for domain-specific-real-time analysis of biomolecular interactions : HIV-1-reverse transcriptase and the primer-template complex

Vorschaubild

Dateien

Zu diesem Dokument gibt es keine Dateien.

Datum

2002

Autor:innen

Famulok, Michael

Herausgeber:innen

Kontakt

ISSN der Zeitschrift

Electronic ISSN

ISBN

Bibliografische Daten

Verlag

Schriftenreihe

Auflagebezeichnung

URI (zitierfähiger Link)
http://nbn-resolving.de/urn:nbn:de:bsz:352-156606
DOI (zitierfähiger Link)
https://doi.org/10.1002/1521-3773(20021115)41:22<4263::AID-ANIE4263>3.0.CO;2-7
ArXiv-ID

Internationale Patentnummer

Angaben zur Forschungsförderung

Projekt

Open Access-Veröffentlichung

Sammlungen

Chemie: Publikationen
Core Facility der Universität Konstanz

Gesperrt bis

Titel in einer weiteren Sprache

Publikationstyp
Zeitschriftenartikel
Publikationsstatus
Published

Erschienen in

Angewandte Chemie International Edition. 2002, 41(22), pp. 4263-4266. ISSN 1433-7851. Available under: doi: 10.1002/1521-3773(20021115)41:22<4263::AID-ANIE4263>3.0.CO;2-7

Zusammenfassung

By fusing an aptamer to a ribozyme, an aptazyme was constructed (see picture) which sensitively and specifically detects the presence of HIV-1 reverse transcriptase (RT). The fusion construct not only serves as a biosensor, but is also well suited for screening lead structures binding to the primer/template binding site of HIV-1 RT.

Zusammenfassung in einer weiteren Sprache

Fachgebiet (DDC)
540 Chemie

Schlagwörter

hammerhead ribozyme, proteins, reverse transcriptase, ribozymes, RNA, RNA–protein interactions

Konferenz

Rezension
undefined / . - undefined, undefined

Forschungsvorhaben

Organisationseinheiten

Zeitschriftenheft

Zugehörige Datensätze in KOPS

Zitieren

ISO 690HARTIG, Jörg S., Michael FAMULOK, 2002. Reporter ribozymes for domain-specific-real-time analysis of biomolecular interactions : HIV-1-reverse transcriptase and the primer-template complex. In: Angewandte Chemie International Edition. 2002, 41(22), pp. 4263-4266. ISSN 1433-7851. Available under: doi: 10.1002/1521-3773(20021115)41:22<4263::AID-ANIE4263>3.0.CO;2-7
BibTex
@article{Hartig2002Repor-15660,
  year={2002},
  doi={10.1002/1521-3773(20021115)41:22<4263::AID-ANIE4263>3.0.CO;2-7},
  title={Reporter ribozymes for domain-specific-real-time analysis of biomolecular interactions : HIV-1-reverse transcriptase and the primer-template complex},
  number={22},
  volume={41},
  issn={1433-7851},
  journal={Angewandte Chemie International Edition},
  pages={4263--4266},
  author={Hartig, Jörg S. and Famulok, Michael}
}
RDF
<rdf:RDF
    xmlns:dcterms="http://purl.org/dc/terms/"
    xmlns:dc="http://purl.org/dc/elements/1.1/"
    xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
    xmlns:bibo="http://purl.org/ontology/bibo/"
    xmlns:dspace="http://digital-repositories.org/ontologies/dspace/0.1.0#"
    xmlns:foaf="http://xmlns.com/foaf/0.1/"
    xmlns:void="http://rdfs.org/ns/void#"
    xmlns:xsd="http://www.w3.org/2001/XMLSchema#" > 
  <rdf:Description rdf:about="https://kops.uni-konstanz.de/server/rdf/resource/123456789/15660">
    <dc:language>eng</dc:language>
    <dcterms:available rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-10-10T10:34:12Z</dcterms:available>
    <dcterms:bibliographicCitation>Ersch. in: Angewandte Chemie / International Edition ; 41 (2002), 22. - S. 4263-4266</dcterms:bibliographicCitation>
    <dc:creator>Famulok, Michael</dc:creator>
    <dspace:isPartOfCollection rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <dc:contributor>Hartig, Jörg S.</dc:contributor>
    <dc:creator>Hartig, Jörg S.</dc:creator>
    <bibo:uri rdf:resource="http://kops.uni-konstanz.de/handle/123456789/15660"/>
    <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2011-10-10T10:34:12Z</dc:date>
    <dc:rights>terms-of-use</dc:rights>
    <dcterms:rights rdf:resource="https://rightsstatements.org/page/InC/1.0/"/>
    <dc:contributor>Famulok, Michael</dc:contributor>
    <foaf:homepage rdf:resource="http://localhost:8080/"/>
    <dcterms:abstract xml:lang="eng">By fusing an aptamer to a ribozyme, an aptazyme was constructed (see picture) which sensitively and specifically detects the presence of HIV-1 reverse transcriptase (RT). The fusion construct not only serves as a biosensor, but is also well suited for screening lead structures binding to the primer/template binding site of HIV-1 RT.</dcterms:abstract>
    <dcterms:issued>2002</dcterms:issued>
    <dcterms:title>Reporter ribozymes for domain-specific-real-time analysis of biomolecular interactions : HIV-1-reverse transcriptase and the primer-template complex</dcterms:title>
    <dcterms:isPartOf rdf:resource="https://kops.uni-konstanz.de/server/rdf/resource/123456789/29"/>
    <void:sparqlEndpoint rdf:resource="http://localhost/fuseki/dspace/sparql"/>
  </rdf:Description>
</rdf:RDF>

Interner Vermerk

xmlui.Submission.submit.DescribeStep.inputForms.label.kops_note_fromSubmitter

Kontakt
URL der Originalveröffentl.

Prüfdatum der URL

Prüfungsdatum der Dissertation

Finanzierungsart

Kommentar zur Publikation

Allianzlizenz
Corresponding Authors der Uni Konstanz vorhanden
Internationale Co-Autor:innen
Universitätsbibliographie
Nein
Begutachtet
Diese Publikation teilen